Infect Dis Clin North Am, 2015 Chronic Lyme disease is a poorly defined diagnosis that is usually given to patients with prolonged, unexplained symptoms or with alternative medical diagnoses. Data do not support the proposition that chronic, treatment-refractory infection with Borrelia burgdorferi is responsible for the many conditions that get labeled as chronic Lyme disease ...
Lantos PM.
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Efficacy of Double-Dose Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-infections: A Report of Three Cases and Retrospective Chart Review [PDF]
Antibiotics, 2020 Three patients with multi-year histories of relapsing and remitting Lyme disease and associated co-infections despite extended antibiotic therapy were each given double-dose dapsone combination therapy (DDD CT) for a total of 7–8 weeks. At the completion
Richard I. Horowitz, Phyllis R. Freeman
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Controversies in Persistent (Chronic) Lyme Disease. [PDF]
J Infus Nurs, 2016 The Centers for Disease Control and Prevention estimates that more than 300 000 new cases of Lyme disease occur each year in the United States and that 10% to 20% of these patients will remain symptomatic despite receiving appropriate antibiotic therapy.
Maloney EL.
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Proof That Chronic Lyme Disease Exists [PDF]
Interdisciplinary Perspectives on Infectious Diseases, 2010 The evidence continues to mount that Chronic Lyme Disease (CLD) exists and must be addressed by the medical community if solutions are to be found. Four National Institutes of Health (NIH) trials validated the existence and severity of CLD. Despite the evidence, there are physicians who continue to deny the existence and severity of CLD, which can ...
Daniel J. Cameron
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Chronic Lyme disease: misconceptions and challenges for patient management [PDF]
Infection and Drug Resistance, 2015 John J HalperinDepartment of Neurosciences, Overlook Medical Center, Summit, NJ, USAAbstract: Lyme disease, infection with the tick-borne spirochete Borrelia burgdorferi, causes both specific and nonspecific symptoms.
Halperin JJ
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Precision medicine: retrospective chart review and data analysis of 200 patients on dapsone combination therapy for chronic Lyme disease/post-treatment Lyme disease syndrome: part 1 [PDF]
International Journal of General Medicine, 2019 Richard I Horowitz,1,2 Phyllis R Freeman2 1Health and Human Services, Tick-Borne Disease Working Group, Washington, DC 20201 USA; 2Hudson Valley Healing Arts Center, Hyde Park, NY 12538, USA Purpose: We collected data from an online survey of 200 of our ...
Horowitz RI, Freeman PR
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Disulfiram—Mitigating Unintended Effects
Antibiotics, 2023 Lyme disease caused by infection with a multitude of vector-borne organisms can sometimes be successfully treated in its very early stages. However, if diagnosis is delayed, this infection can become disseminated and, like another spirochetal infection ...
Martha M. Grout, Kenneth B. Mitchell
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The social representations of diagnosing Lyme disease
PLoS ONE, 2023 Social science studies on the controversy surrounding Lyme disease (LD) focused on the opposition between the “mainstream” and biomedical approach on one side and the “Lyme-literate” one on the other side, the latter claiming the existence of the chronic
C. Puppo +5 more
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Detecting Borrelia Spirochetes: A Case Study With Validation Among Autopsy Specimens
Frontiers in Neurology, 2021 The complex etiology of neurodegenerative disease has prompted studies on multiple mechanisms including genetic predisposition, brain biochemistry, immunological responses, and microbial insult.
Shiva Kumar Goud Gadila +8 more
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