Infect Dis Clin North Am, 2015 Chronic Lyme disease is a poorly defined diagnosis that is usually given to patients with prolonged, unexplained symptoms or with alternative medical diagnoses. Data do not support the proposition that chronic, treatment-refractory infection with Borrelia burgdorferi is responsible for the many conditions that get labeled as chronic Lyme disease ...
Lantos PM.
europepmc +6 more sources
Chronic Lyme disease: misconceptions and challenges for patient management [PDF]
Infection and Drug Resistance, 2015 John J HalperinDepartment of Neurosciences, Overlook Medical Center, Summit, NJ, USAAbstract: Lyme disease, infection with the tick-borne spirochete Borrelia burgdorferi, causes both specific and nonspecific symptoms.
Halperin JJ
doaj +3 more sources
The Persistent Lyme Disease: “True Chronic Lyme Disease” rather than “Post-treatment Lyme Disease Syndrome” [PDF]
Journal of Global Infectious Diseases, 2018 Alexis Lacout +3 more
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Controversies in Persistent (Chronic) Lyme Disease. [PDF]
J Infus Nurs, 2016 The Centers for Disease Control and Prevention estimates that more than 300 000 new cases of Lyme disease occur each year in the United States and that 10% to 20% of these patients will remain symptomatic despite receiving appropriate antibiotic therapy.
Maloney EL.
europepmc +4 more sources
Efficacy of Double-Dose Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-infections: A Report of Three Cases and Retrospective Chart Review [PDF]
Antibiotics, 2020 Three patients with multi-year histories of relapsing and remitting Lyme disease and associated co-infections despite extended antibiotic therapy were each given double-dose dapsone combination therapy (DDD CT) for a total of 7–8 weeks. At the completion
Richard I. Horowitz, Phyllis R. Freeman
doaj +2 more sources
Antiphospholipid antibodies in acute and post-treatment Lyme disease [PDF]
Infection and ImmunityAcute Lyme disease is caused by a Borrelia infection and typically responds to antibiotic treatment, but post-infectious chronic symptoms are common. The precise origin of these post-treatment symptoms is unknown; dysregulation of immune responses raised
Muskan Shrestha +10 more
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Chronic Lyme disease: the controversies and the science [PDF]
Expert Review of Anti-Infective Therapy, 2011 The diagnosis of chronic Lyme disease has been embroiled in controversy for many years. This is exacerbated by the lack of a clinical or microbiologic definition, and the commonality of chronic symptoms in the general population. An accumulating body of evidence suggests that Lyme disease is the appropriate diagnosis for only a minority of patients in ...
Paul M Lantos
exaly +3 more sources
Proof That Chronic Lyme Disease Exists [PDF]
Interdisciplinary Perspectives on Infectious Diseases, 2010 The evidence continues to mount that Chronic Lyme Disease (CLD) exists and must be addressed by the medical community if solutions are to be found. Four National Institutes of Health (NIH) trials validated the existence and severity of CLD. Despite the evidence, there are physicians who continue to deny the existence and severity of CLD, which can ...
Daniel J. Cameron
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Reassessing Chronic Lyme Disease and Post-Treatment Lyme Disease Syndrome as Focal Infections. [PDF]
CureusThe complete clinical spectrum of Lyme borreliosis has been recognized for nearly 50 years, yet its diagnosis remains challenging due to the heterogeneity of symptoms. While many symptoms are likely nonspecific, a recurring cluster, including severe fatigue, brain fog, cognitive decline, memory impairment, joint and muscle pain, limb numbness ...
Lakos A +4 more
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Promoting a Positive Relationship Between Physicians and Patients with Lyme Disease During Pregnancy and Parenthood [PDF]
PathogensPatients with Lyme disease often face uncertainty when navigating the healthcare system during pregnancy and when seeking healthcare for their children exposed to Lyme disease in utero. Little is known about these families’ experiences.
Emma T. Hickman +3 more
doaj +2 more sources