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Perspectives on “Chronic Lyme Disease”
American Journal of Medicine, 2008There is much controversy about the treatment of Lyme disease with respect to 2 poorly defined entities: "chronic Lyme disease" and "posttreatment Lyme disease syndrome." In the absence of direct evidence that these conditions are the result of a persistent infection, some mistakenly advocate extended antibiotic therapy (>/=6 months), which can do ...
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Chronic Neurologic Manifestations of Lyme Disease
New England Journal of Medicine, 1990Lyme disease, caused by the tick-borne spirochete Borrelia burgdorferi, is associated with a wide variety of neurologic manifestations. To define further the chronic neurologic abnormalities of Lyme disease, we studied 27 patients (age range, 25 to 72 years) with previous signs of Lyme disease, current evidence of immunity to B.
Allen Steere +2 more
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Clinical Reviews in Allergy and Immunology, 2021
Lyme disease is an infection caused by Borrelia burgdorferi sensu lato, which is transmitted to humans through the bite of an infected Ixodes tick. The majority of patients recover without complications with antibiotic therapy. However, for a minority of patients, accompanying non-specific symptoms can persist for months following completion of therapy.
Eugene D Shapiro +2 more
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Lyme disease is an infection caused by Borrelia burgdorferi sensu lato, which is transmitted to humans through the bite of an infected Ixodes tick. The majority of patients recover without complications with antibiotic therapy. However, for a minority of patients, accompanying non-specific symptoms can persist for months following completion of therapy.
Eugene D Shapiro +2 more
exaly +3 more sources
AbstractThe term 'chronic Lyme disease' is used to describe vastly different patient populations, including patients with objective manifestations of late Lyme disease, patients with post-Lyme disease syndrome, and patients with nonspecific signs and symptoms of unclear cause who were diagnosed based on unproven and non-validated clinical and ...
A. Marques
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Chronic polyneuropathy and Lyme disease
European Journal of Neurology, 2006Infection of the peripheral nervous system with Borrelia burgdorferi can present as a cranial neuropathy or radiculopathy with cerebrospinal fluid (CSF) pleocytosis and intrathecal antibody production against B. burgdorferi, or as an asymmetric peripheral neuropathy with acrodermatitis chronica atrophicans (ACA) and normal CSF findings.
A, Mygland, T, Skarpaas, U, Ljøstad
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Chronic Lyme Disease And The ‘Axis of Evil’
Future Microbiology, 2008Lyme disease is a controversial illness, and the existence of chronic Lyme disease induced by persistent infection with the Lyme spirochete, Borrelia burgdorferi, is the subject of continued debate. A recent publication defined the 'Axis of Evil' in this controversy as physicians who treat patients with needlessly prolonged courses of antibiotics ...
Raphael B, Stricker, Lorraine, Johnson
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Medical Clinics of North America, 2002
This article reviews the late and chronic manifestations of Lyme disease. Special attention is given to the chronic manifestations of the disease, detailing its pathogenesis, clinical spectrum, and laboratory criteria for the diagnosis. Based on experimental evidence and experience, approaches to the successful treatment of the late and chronic disease
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This article reviews the late and chronic manifestations of Lyme disease. Special attention is given to the chronic manifestations of the disease, detailing its pathogenesis, clinical spectrum, and laboratory criteria for the diagnosis. Based on experimental evidence and experience, approaches to the successful treatment of the late and chronic disease
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Nervous system Lyme disease, chronic Lyme disease, and none of the above
Acta Neurologica Belgica, 2015Lyme borreliosis, infection with the tick-borne spirochete Borrelia burgdorferi sensu lato, causes nervous system involvement in 10-15 % of identified infected individuals. Not unlike the other well-known spirochetosis, syphilis, infection can be protracted, but is microbiologically curable in virtually all patients, regardless of disease duration ...
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Chronic Lyme disease: Fact or fiction?
Joint Bone Spine, 2014Joint Bone Spine - In Press.Proof corrected by the author Available online since mardi 25 fevrier ...
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Spirochetes in the Spleen of a Patient with Chronic Lyme Disease
American Journal of Clinical Pathology, 1989A 54-year-old man had intermittent evening fever, arthralgia, transient erythematous macular eruption on the skin, and splenomegaly of two year's duration. Immunofluorescence tests for Borrelia burgdorferi serum antibodies had positive results, but G-penicillin treatment was ineffective.
CIMMINO, MARCO AMEDEO +3 more
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