Results 61 to 70 of about 14,941 (180)
ABSTRACT Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is caused by pathogenic variants in the GATA3 gene located on chromosome 10p14. Here we present a 10‐year‐old girl with HDR syndrome who also has oligoarticular juvenile idiopathic arthritis (JIA).
Lauren N. Meiss +8 more
wiley +1 more source
Dysautonomia following Lyme disease: a key component of post-treatment Lyme disease syndrome?
Dysautonomia, or dysfunction of the autonomic nervous system (ANS), may occur following an infectious insult and can result in a variety of debilitating, widespread, and often poorly recognized symptoms.
Brittany L. Adler +3 more
doaj +1 more source
Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu +9 more
wiley +1 more source
Review of evidence for immune evasion and persistent infection in Lyme disease
Keith Berndtson Park Ridge MultiMed, Park Ridge, IL, USA Abstract: Is chronic illness in patients with Lyme disease caused by persistent infection? Three decades of basic and clinical research have yet to produce a definitive answer to this question ...
Berndtson K
doaj
Current treatments for severe lupus nephritis are limited by side effects due to poor drug targeting. This review explores how smart nanomaterials—like liposomes and biomimetic carriers—can precisely deliver drugs to overactive immune cells and the kidneys. These nanotherapeutics enhance efficacy, reduce toxicity, and enable combination strategies. The
Cheng Zhou +6 more
wiley +1 more source
Peruvian frogs underwent a climate‐driven range expansion into deglaciating mountains, exposing themselves and their fungal pathogen Batrachochytrium dendrobatidis (Bd) to challenging new thermal environments. Bd has dispersed extensively in these new habitats, and elevation may mediate the apparent sublethal impacts of infection for frogs.
Emma Steigerwald +6 more
wiley +1 more source
Summary A 9‐year‐old male castrated Standardbred was presented for evaluation of a comminuted right front first phalanx fracture. On initial clinical examination, mild haemoconcentration and increased vital parameters were noted. After overnight hospitalisation, the horse underwent general anaesthesia for surgical fracture repair.
I. Lutvikadic, K. Hopster, B. Driessen
wiley +1 more source
Molecular detection of pathogens in an equine fever diagnostic panel: 2019–2023
Abstract Background A common diagnostic approach for febrile horses is to test for a panel of potential pathogens. Panels are curated by expert opinion and vary between diagnostic laboratories. Objectives To report the results of a newly developed equine fever diagnostic panel (EFDP) between 2019 and 2023 and evaluate the frequency of positive results.
Toby L. Pinn‐Woodcock +3 more
wiley +1 more source
ABSTRACT Objective Climate change is contributing to increasing rates of vector‐borne diseases, affecting global population health. As the largest group of regulated health professionals, nurses play an integral role in climate‐related health challenges.
Shannon Y. Vandenberg +3 more
wiley +1 more source

