Transcriptomic and miRNA-Target Pathway Analysis of the DLK1-DIO3 Imprinted microRNA Cluster in Chronic Lymphocytic Leukemia. [PDF]
Markopoulos GS +7 more
europepmc +1 more source
Extragenital <i>Mycoplasma hominis</i> infection following obinutuzumab therapy in a patient with chronic lymphocytic leukemia. [PDF]
Benandi K, Blanton LS.
europepmc +1 more source
EHA Guidelines on management of chronic lymphocytic leukemia and Richter transformation. [PDF]
Eichhorst B +13 more
europepmc +1 more source
ZMYM3 mutations modulate histone acetylation and cooperate with NOTCH1 mutations in chronic lymphocytic leukemia. [PDF]
Rodríguez-Sánchez A +14 more
europepmc +1 more source
Chronic Lymphocytic Leukemia: Molecular Pathologies and Therapeutic Strategies. [PDF]
Meza K +9 more
europepmc +1 more source
Summary Most patients treated for chronic lymphocytic leukaemia (CLL) fail to achieve measurable residual disease (MRD) negativity. The role of maintenance with the immunomodulatory drug lenalidomide in these patients is unclear. A randomised multicentre phase III trial (ACTRN12610000060044) was conducted in Australia and France to assess the effect of
Thérèse Aurran‐Schleinitz +45 more
wiley +1 more source
Resistance pathways and next-generation treatments in chronic lymphocytic leukemia. [PDF]
Bellemrrabet R +7 more
europepmc +1 more source
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Atypical chronic lymphocytic leukemia with biallelic 13Q deletion. [PDF]
Roldán Galiacho V +3 more
europepmc +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source

