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OnabotulinumtoxinA for Chronic Migraine
Headache: The Journal of Head and Face Pain, 2012In 1992, Binder, a facial plastic surgeon in Los Angeles, first noted migraine improvement in a patient he was injecting with onabotulinumtoxinA for wrinkles.At the American Headache Society meeting in 1998, Binder and colleagues presented the first poster on onabotulinumtoxinA treatment in patients with migraine.
Andrew, Blumenfeld, Randolph W, Evans
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Current Pain and Headache Reports, 2010
Chronic migraine is defined in different ways. The most commonly used definition is headache on more than 15 days per month in patients with migraine. Chronic migraine is difficult to treat and requires a multidisciplinary approach. Only two pharmacological treatments have been shown to be effective in placebo-controlled randomized trials: topiramate ...
Diener, Hans Christoph +2 more
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Chronic migraine is defined in different ways. The most commonly used definition is headache on more than 15 days per month in patients with migraine. Chronic migraine is difficult to treat and requires a multidisciplinary approach. Only two pharmacological treatments have been shown to be effective in placebo-controlled randomized trials: topiramate ...
Diener, Hans Christoph +2 more
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Emerging treatment for chronic migraine and refractory chronic migraine
Expert Opinion on Emerging Drugs, 2012Chronic migraine (CM), the suffering of 15 or more headache days with at least 8 of these migraine days, afflicts 1.3% - 5.1% of the global population. CM is the most common disorder faced by experts in tertiary headache centers. When resistant to conventional medical treatment and prophylactic medication this condition is known as refractory chronic ...
Luana Lionetto +10 more
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Neurology India, 2021
Background: Chronic migraine is an under-recognized and under-treated disorder. A greater understanding of the pathophysiology of migraine and transformation to chronic migraine has led to the first targeted treatments for chronic migraine.
Catriona L, Gribbin +2 more
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Background: Chronic migraine is an under-recognized and under-treated disorder. A greater understanding of the pathophysiology of migraine and transformation to chronic migraine has led to the first targeted treatments for chronic migraine.
Catriona L, Gribbin +2 more
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Headache, 2021
To evaluate the long‐term effectiveness, safety, and tolerability of erenumab in a real‐world migraine population, looking for putative predictors of responsiveness.
P. Barbanti +14 more
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To evaluate the long‐term effectiveness, safety, and tolerability of erenumab in a real‐world migraine population, looking for putative predictors of responsiveness.
P. Barbanti +14 more
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Headache, 2021
To describe headache characteristics, medication use, disability, and quality of life in a large patient cohort from the United States who have chronic migraine (CM) and medication overuse headache (MOH).
T. Schwedt +12 more
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To describe headache characteristics, medication use, disability, and quality of life in a large patient cohort from the United States who have chronic migraine (CM) and medication overuse headache (MOH).
T. Schwedt +12 more
semanticscholar +1 more source
Current Pain and Headache Reports, 2011
Chronic migraine typically evolves from episodic migraine over months to years in susceptible individuals. Headaches increase in frequency over time, becoming less intense but more disabling and less responsive to treatment. Results of electrophysiologic and functional imaging studies indicate that chronic migraine is associated with abnormalities in ...
Sheena K, Aurora +2 more
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Chronic migraine typically evolves from episodic migraine over months to years in susceptible individuals. Headaches increase in frequency over time, becoming less intense but more disabling and less responsive to treatment. Results of electrophysiologic and functional imaging studies indicate that chronic migraine is associated with abnormalities in ...
Sheena K, Aurora +2 more
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Neuroimaging in chronic migraine
Neurological Sciences, 2010In chronic migraine, many neuroimaging studies with advanced techniques showed abnormalities in several brain areas involved in pain processing. The structural and functional dysfunctions are reported in cerebral areas localized in the brainstem and in the lateral and medial pain pathways.
Luisa, Chiapparini +3 more
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The lesson of chronic migraine
Neurological Sciences, 2015The hypothesis that central sensitization/allodynia is the common final mechanism responsible for the progression of migraine pain is supported by the possibility of tracing back to allodynic mechanisms the action of the main risk factors for chronic migraine validated by the recent literature.
Bonavita Vincenzo, De Simone Roberto.
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Cephalalgia, 2020
Introduction Acute medication overuse is prevalent in patients with migraine. Methods In three phase 3, double-blind, randomized, placebo-controlled studies, patients with episodic migraine (EVOLVE-1 and EVOLVE-2) or chronic migraine (REGAIN) were ...
D. Dodick +7 more
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Introduction Acute medication overuse is prevalent in patients with migraine. Methods In three phase 3, double-blind, randomized, placebo-controlled studies, patients with episodic migraine (EVOLVE-1 and EVOLVE-2) or chronic migraine (REGAIN) were ...
D. Dodick +7 more
semanticscholar +1 more source