Results 91 to 100 of about 188,451 (293)

miR-181a Post-Transcriptionally Downregulates Oncogenic RalA and Contributes to Growth Inhibition and Apoptosis in Chronic Myelogenous Leukemia (CML)

open access: yesPLoS ONE, 2012
MicroRNAs (miRNAs) are a class of short RNAs that regulate gene expression through either translational repression or mRNA cleavage. miRNA-181a (miR-181a), one of the many miRNAs conserved among vertebrates, is differentially expressed in a variety of ...
J. Fei   +3 more
semanticscholar   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, Volume 19, Issue 12, Page 3548-3577, December 2025.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Review of clinical, cytogenetic, and molecular aspects of Ph-negative CML [PDF]

open access: yes, 1991
Between 1985 and 1989, many cases of Philadelphia (Ph) chromosome negative chronic myelogenous leukemia (CML) were reported. For this review, the following selection criteria were used: the original articles on Ph-negative cases should provide clinical ...
Grosveld, G.C. (Gerard)   +2 more
core   +1 more source

mRNA Cancer Vaccines: From Pandemic Paradigm to Personalized Oncology Therapeutics

open access: yesCancer Innovation, Volume 4, Issue 6, December 2025.
This review highlights the transformative potential of mRNA cancer vaccines, leveraging technological advancements in nucleotide modification, lipid nanoparticle delivery, and AI‐driven neoantigen selection to enhance vaccine stability, immunogenicity, and personalization.
Bo Yang, Juan Liu, Yang Li, Xiaoxuan Liu
wiley   +1 more source

Potential of Bacillus subtilis lipopeptides in anti-cancer I: induction of apoptosis and paraptosis and inhibition of autophagy in K562 cells

open access: yesAMB Express, 2018
The lipopeptide iturin from Bacillus subtilis has been found to have a potential inhibitory effect on breast cancer, alveolar adenocarcinoma, renal carcinoma, and colon adenocarcinoma. In this study, the potential of B.
Haobin Zhao   +9 more
doaj   +1 more source

A patient with maculopapular rash and lichenoid skin damage caused by ponatinib

open access: yesJournal of International Medical Research, 2020
Tyrosine kinase inhibitors (TKIs) are invaluable for the treatment of patients with chronic myelogenous leukemia. Although TKIs are generally better tolerated than traditional chemotherapy, dermatologic side effects are common and present a significant ...
Ingrid Anna Teigen   +2 more
doaj   +1 more source

Estimating the prevalence of hematological malignancies and precursor conditions using data from Haematological Malignancy Research Network (HMRN) [PDF]

open access: yes, 2016
Objective: Well-established cancer registries that routinely link to death registrations can estimate prevalence directly by counting patients alive at a particular point in time (observed prevalence).
Crouch, Simon   +4 more
core   +1 more source

Acute Myeloid Leukemia Secondary to Radiation Therapy for Rectal Cancer: A Case Report

open access: yesCancer Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background Therapy‐related AML (t‐AML) is a subtype of acute myeloid leukemia (AML) that arises in the bone marrow and primarily affects white blood cells. It is associated with prior exposure to cytotoxic agents, including chemotherapy and radiotherapy. The risk of the disease increases with age and treatment intensity.
Ahmad Alkhaledi   +4 more
wiley   +1 more source

Chronic myelogenous leukemia occurring in a chronic lymphocytic leukemia patient

open access: yesClinical Case Reports, 2018
Key Clinical Message Occurrence of two different hematological malignancies is very infrequent, and it is nevertheless important not to neglect basic examinations in patients follow‐up.
Jenny Beaud   +3 more
doaj   +1 more source

Subsequent Primary Hematologic Malignancies in a 21‐Year‐Old Retinoblastoma Survivor: Case Report Study

open access: yesCancer Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background Retinoblastoma (RB) is a malignant eye tumor that predominantly affects children. Although survival rates have improved significantly due to advancements in treatment, subsequent malignant neoplasms (SMNs) continue to be major causes of death in both heritable and non‐heritable RB cases.
Elham Karimi   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy