Results 181 to 190 of about 32,475 (204)
Some of the next articles are maybe not open access.
Clinical Journal of Oncology Nursing, 2005
Chronic myelogenous leukemia (CML) represents about 14% of all leukemias and occurs with a frequency of about 1 in 100,000. It is rare in children. Symptoms include fatigue, weight loss, sweating, and abdominal discomfort from an enlarged spleen. The white blood cell count can range from 100-600 ul.
openaire +3 more sources
Chronic myelogenous leukemia (CML) represents about 14% of all leukemias and occurs with a frequency of about 1 in 100,000. It is rare in children. Symptoms include fatigue, weight loss, sweating, and abdominal discomfort from an enlarged spleen. The white blood cell count can range from 100-600 ul.
openaire +3 more sources
Cancer, 1978
Chronic myelogenous leukemia (CML) is a relatively rare disease, with a number of features that make it especially suitable for observations on leukemogenesis in man. These include known etiologic agents, often a prolonged preclinical and active stage, cells with identifiable morphological and histochemical characteristics and the presence of the ...
openaire +3 more sources
Chronic myelogenous leukemia (CML) is a relatively rare disease, with a number of features that make it especially suitable for observations on leukemogenesis in man. These include known etiologic agents, often a prolonged preclinical and active stage, cells with identifiable morphological and histochemical characteristics and the presence of the ...
openaire +3 more sources
Autografting for chronic myelogenous leukemia
Current Opinion in Hematology, 1995Two thirds of patients with chronic myelogenous leukemia do not have suitable donors for allogeneic transplantation. As for other leukemias, autografting may potentially be curative, because normal Ph- hematopoietic stem cells persist in the marrow and blood of patients with chronic myelogenous leukemia.
Ravi Bhatia, Catherine M. Verfaillie
openaire +2 more sources
Current Cancer Therapy Reviews, 2009
Chronic myelogenous leukemia, BCR-ABL1+ (CML), is a myeloproliferative neoplasm defined by the presence of the BCR-ABL fusion gene produced by the t(9;22)(q32;q11) cytogenetic abnormality. CML manifests clinically as leukocytosis with circulating immature granulocytic precursors and splenomegaly.
openaire +2 more sources
Chronic myelogenous leukemia, BCR-ABL1+ (CML), is a myeloproliferative neoplasm defined by the presence of the BCR-ABL fusion gene produced by the t(9;22)(q32;q11) cytogenetic abnormality. CML manifests clinically as leukocytosis with circulating immature granulocytic precursors and splenomegaly.
openaire +2 more sources
Priapism in chronic myelogenous leukemia
The Indian Journal of Pediatrics, 1992Twelve year old boy, was admitted at the All India Institute of Medical Sciences, New Delhi in March 1990 with a history of left hypochondrial mass for six years and priapism for 2 days. He had an episode of priapi.~m one month ago, which spontaneously subsided within 8 hours Examination revealed mild pallor, sternal tenderness and gcneralized ...
Poonam Bhatia +4 more
openaire +2 more sources
Chronic myelogenous leukemia: A review
The American Journal of Medicine, 1996Chronic myelogenous leukemia (CML) is a chronic myeloproliferative disorder with an initially chronic course lasting for 3-5 years. It eventually transforms into accelerated and blastic phases, which are generally fatal. CML was one of the first diseases in which a specific chromosomal abnormality was identified, a t(9;22)(q34;q11) or Philadelphia ...
Jorge E. Cortes +2 more
openaire +2 more sources
Chronic myelogenous leukemia in children
The Journal of Pediatrics, 1953Summary Observations were reported on fifteenchildren with chronic myelogenous leukemia. During infancy the clinical manifestations were chiefly of a hemorrhagic character and associated with thrombocytopenia. In older children the disease was essentially the same as seen in adults. The best results in therapy were obtained by x-ray irradiation given
Jean V. Cooke, Jean V. Cooke
openaire +3 more sources
2014
The impact of age as a poor prognostic factor in chronic myeloid leukemia (CML) has been well described. In the interferon era, elderly patients diagnosed with CML in chronic phase had shorter survival compared to younger patients. With the advent of targeted therapy with imatinib, studies described consistently improved responses in elderly late ...
Andreas Hochhaus, Susanne Saussele
openaire +2 more sources
The impact of age as a poor prognostic factor in chronic myeloid leukemia (CML) has been well described. In the interferon era, elderly patients diagnosed with CML in chronic phase had shorter survival compared to younger patients. With the advent of targeted therapy with imatinib, studies described consistently improved responses in elderly late ...
Andreas Hochhaus, Susanne Saussele
openaire +2 more sources
BIOLOGY OF CHRONIC MYELOGENOUS LEUKEMIA
Hematology/Oncology Clinics of North America, 1998This article reviews the biology of chronic myelogenous leukemia (CML) and its effect on the process of hematopoiesis. The relevance of the BCR-ABL fusion protein as well as murine models are also discussed. CML has been studied more extensively than any other malignancy, yet the correlation between the clinical symptoms of chronic phase CML and the ...
openaire +3 more sources
Hypercalcemia in Chronic Myelogenous Leukemia
New England Journal of Medicine, 1970SERUM calcium concentration may be elevated in any neoplastic disorder associated with bone destruction, either primary or metastatic. However, relatively few cases of hypercalcemia and bone destruction have been observed in conjunction with leukemia.1 2 3 4 5 6 7 8 9 In the majority of previously reported cases of hypercalcemia, the patients have had ...
Harold S. Ballard, Aaron J. Marcus
openaire +3 more sources