Results 11 to 20 of about 41,447 (182)

Chronic myelogenous leukemia on target [PDF]

Cancer Medicine, 2018
Chronic myelogenous leukemia (CML) is commonly treated with tyrosine kinase inhibitors (TKIs) that inhibit the pro‐leukemic activity of the BCR‐ABL1 oncoprotein.
Veronika Némethová, Filip Rázga
doaj   +3 more sources

Chronic myelogenous leukemia in Libya

South Asian Journal of Cancer, 2012
Itrat Mehdi, Arshad Hussain Kashmiri
doaj   +3 more sources

Pathogenesis of chronic myelogenous leukemia

Haematologica, 1994
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G Bergamaschi, V Rosti
doaj   +4 more sources

Chronic Myelogenous Leukemia [PDF]

Journal of the National Comprehensive Cancer Network, 2012
Chronic myelogenous leukemia (CML) is the one of the most common chronic myeloproliferative disorders. It has become the paradigmatic disease for molecular diagnosis and monitoring for several reasons: (1) CML has a unitary molecular definition, requiring the demonstration of the t(9;22)(q34;q11) chromosomal translocation or its product, the BCR-ABL ...
Susan, O'Brien, Camille N, Abboud, Mojtaba, Akhtari, Jessica, Altman, Ellin, Berman, Daniel J, DeAngelo, Steven, Devine, Amir T, Fathi, Jason, Gotlib, Madan, Jagasia, Joseph O, Moore, Javier, Pinilla-Ibarz, Jerald P, Radich, Vishnu V B, Reddy, Neil P, Shah, Paul J, Shami, B Douglas, Smith, David S, Snyder, Meir, Wetzler, Furhan, Yunus   +19 more
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Juvenile Chronic Myelogenous Leukemia [PDF]

American Journal of Clinical Pathology, 1996
Juvenile chronic myelogenous leukemia (JCML) is an aggressive myeloproliferative disorder of childhood that differs both clinically and pathologically from adult type, Philadelphia chromosome positive chronic myelogenous leukemia, and from the other myeloproliferative disorders that are more common in adulthood.
J L, Hess, M M, Zutter, R P, Castleberry, P D, Emanuel   +3 more
openaire   +2 more sources

Transcriptome sequencing of hematopoietic stem cells and chronic myelgenous leukemia stem cells

Genomics Data, 2016
Dipeptide species are accumulated in the chronic myelogenous leukemia (CML) stem cells [1]. To investigate the molecular mechanisms of the accumulation of dipeptide species in CML stem cells, we performed transcriptome sequencing of long-term stem cells,
Junil Kim, Seong-Jin Kim, Kazuhito Naka
doaj   +1 more source

Ponatinib-associated panniculitis: Case report and review of the literature

Cancer Treatment and Research Communications, 2021
Ponatinib is a tyrosine kinase inhibitor (TKI) approved for the treatment of Philadelphia chromosome-positive chronic myelogenous leukemia and acute lymphoblastic leukemia. Common adverse effects of ponatinib include neutropenia, arterial thrombosis, and
Daniel Antwi-Amoabeng, Joban Ghuman, Jasmine Ghuman, Bryce D. Beutler, Mark B. Ulanja, Kevin Kuriakose, Aaron Bowman   +6 more
doaj   +1 more source

A case of chronic myelogenous leukemia with the T315I mutation who progressed to myeloid blast phase and was successfully treated with asciminib

Clinical Case Reports, 2022
Patients with chronic myelogenous leukemia (CML) harboring the T315I mutation who progress to blast phase CML while on ponatinib may be successfully treated with asciminib monotherapy following induction therapy with cytotoxic chemotherapy.
Sarah Tomassetti, Jennifer Lee, Xin Qing
doaj   +1 more source

Permanent Sensorineural Deafness in a Patient with Chronic Myelogenous Leukemia Secondary to Intracranial Hemorrhage

Case Reports in Hematology, 2013
A 52-year-old male presented with tinnitus and fullness in left ear for one day. Workup revealed a white blood cell count of 685×103/μL with marked increase in granulocyte series and myeloid precursors on peripheral smear.
Sakshi Kapur, Michael Wax, Levin Miles, Adnan Hussain   +3 more
doaj   +1 more source

A case of chronic myelogenous leukemia in pregnancy characterized by a complex translocation t(9;22;11)(q34;q11.2;q13)

Hematology Reports, 2011
The management of chronic myelogenous leukemia during pregnancy requires balancing the well-being of the mother with that of the fetus. We report a case of a 26-year-old lady who was diagnosed with chronic myelogenous leukemia (CML) at 15 weeks gestation
Surachit Kumar, Mariya Apostolova, Paul V. Woolley   +2 more
doaj   +1 more source