Results 31 to 40 of about 39,121 (223)

SQUAMOUS CELL CARCINOMA AS A LATE COMPLICATION OF CHRONIC OSTEOMYELITIS

Journal of Nepal Medical Association, 2003
Squamous cell carcinoma is a rare but well documented complication of chronic osteomyelitis. With the advent of antibiotics, better health care delivery to the people and improving socioeconomic conditions, the incidence of squamous cell carcinoma ...
Shishir Lakhey, M Lakhey, B P Shrestha
doaj   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Primary Bone Lymphoma of Humerus Culminated to Shoulder Disarticulation-Astray of Diagnosis [PDF]

Journal of Clinical and Diagnostic Research, 2019
In the horizon of knowledge, there is dearth of documentation depicting the incidence of Primary Bone Lymphoma (PBL) being delayed/misdiagnosed as chronic osteomyelitis, which entails that this case report is of more magnitude.
Pankaj Kumar Mishra, Sujeet Mishra, Deepak Singh Maravi, Sanjiv Gaur, Ashish Gohiya   +4 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

A multifaceted osteomyelitis: radiological diagnosis

Гений oртопедии, 2020
Introduction Analysis of the literature and our own data confirm that changes in bone structure in chronic osteomyelitis vary in extension and severity, the boundaries of which are very difficult to determine.
Galina V. Diachkova, Konstantin A. Diachkov, Tat'iana A. Larionova, Nikolai M. Kliushin, Alexander L. Shastov   +4 more
doaj   +1 more source

Current research progress of local drug delivery systems based on biodegradable polymers in treating chronic osteomyelitis

Frontiers in Bioengineering and Biotechnology, 2022
Chronic osteomyelitis is one of the most challenging diseases in orthopedic treatment. It is usually treated with intravenous antibiotics and debridement in clinical practice, which also brings systemic drug side effects and bone defects.
Yixiu Liu, Yixiu Liu, Xu Li, Xu Li, A. Liang, A. Liang   +5 more
doaj   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

MR Findings of Squamous Cell Carcinoma Arising from Chronic Osteomyelitis of the Tibia: A Case Report

대한영상의학회지, 2016
Malignant transformation is a rare and late complication of untreated chronic osteomyelitis. Known radiographic findings of the malignant transformation of chronic osteomyelitis are osteolytic or mixed sclerotic and osteolytic lesions with or without ...
Donghwa Han, Jihae Lee, Woo Ho Cho, Jae Hyung Kim, Myeong Ja Jeong, Soung Hee Kim, Ji-Young Kim, Soo Hyun Kim, Mi-Jin Kang, Kyung Eun Bae   +9 more
doaj   +1 more source

The Positive Approach to Chronic Osteomyelitis [PDF]

Journal of Occupational and Environmental Medicine, 1959
The extent of the pathological process is underestimated if the condition is regarded only as an infection of bone : many other tissues are affected, including periosteum, muscle, fascia and skin. When sclerosis and fibrosis supervene, strangulation of the small blood vessels causes local tissue anaemia.
openaire   +2 more sources

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source