Objective This study analyzed longitudinal trajectories of soluble Flt1 (sFlt1) levels, placenta growth factor (PlGF) levels, and sFlt1:PlGF ratios in a cohort of pregnant patients with systemic lupus erythematosus (SLE). Methods Blood samples were collected (14–18, 24–26, 30–32, 34–36, and 38–40 weeks), stored at −80°C, and evaluated for serum levels ...
Nilson R. de Jesús+7 more
wiley +1 more source
Effects of stress and relaxation on central pain modulation in chronic whiplash and fibromyalgia patients compared to healthy controls [PDF]
Background: Compelling evidence has demonstrated that impaired central pain modulation contributes to persistent pain in patients with chronic whiplash associated disorders (WAD) and fibromyalgia (FM).
Coppieters, Iris+6 more
core
Exercise Increases Pressure Pain Tolerance but Not Pressure and Heat Pain Thresholds in Healthy Young Men [PDF]
Background: Exercise causes an acute decrease in the pain sensitivity known as exercise-induced hypoalgesia (EIH), but the specificity to certain pain modalities remains unknown.
Bartholomew+39 more
core +2 more sources
A Triage Approach to Managing a Two Year Wait-List in a Chronic Pain Program
OBJECTIVE: Individuals with chronic pain referred to specialist chronic pain management programs frequently wait months to years for assessment and care. In the authors' pain management program, approximately 600 patients are on the waiting list.
Alexander J Clark+3 more
doaj +1 more source
Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
wiley +1 more source
Is traumatic and non-traumatic neck pain associated with brain alterations? : a systematic review [PDF]
Background: Chronic neck pain affects 50% - 85% of people who have experienced an acute episode. This transition and the persistence of chronic complaints are believed to be mediated by brain alterations among different central mechanisms.
Caeyenberghs, Karen+5 more
core
Transition from Acute to Chronic Pain: Evaluating Risk for Chronic Postsurgical Pain.
BACKGROUND The pathophysiology of pain involves complex nervous system interactions after initial noxious stimuli. When stimuli persist, biochemical and structural changes occur in the nociceptive pathways of the central and peripheral nervous systems ...
G. Fregoso+3 more
semanticscholar +1 more source
Objective We aimed to assess whether high‐sensitivity C‐reactive protein (hsCRP) levels could predict the development of psoriatic arthritis (PsA) in patients with psoriasis. Methods We analyzed data from a prospective cohort of patients with psoriasis without PsA at enrollment.
Lihi Eder+5 more
wiley +1 more source
Evaluation of back education programme at the Medical Rehabilitation Unit, Palmerston North Hospital : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]
Chronic low back pain is a significant health care problem and is frequently one of the most difficult conditions to treat. For the individual, chronic low back pain evolves into a constellation of problems involving psychological and behavioural ...
Williams, Mei Wah
core
BACKGROUND AND OBJECTIVES: Sickle cell disease is considered the most common hereditary disorder in Brazil. The chronic pain resulting from some complications of sickle cell disease is still poorly understood, inadequately described, and under-researched.
Lais Costa Akcelrud Durão+4 more
doaj +1 more source