Results 181 to 190 of about 878,103 (295)

Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin

open access: yesAdvanced Healthcare Materials, EarlyView.
Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis   +6 more
wiley   +1 more source

Toward Noninvasively Imaging pH at the Surface of Implanted Orthopedic Devices in Live Rabbits Using X‐ray Excited Luminescence Chemical Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
Imaging pH in a live rabbit at the surface of a sensor‐coated titanium plate using X‐ray excited luminescent chemical imaging (XELCI). A raster scanning X‐ray beam generates radioluminescence from a spot on the sensor, and the luminescence passes through the tissue and is collected at two wavelengths to determine local pH.
Unaiza Uzair   +6 more
wiley   +1 more source

The relationship between abnormal glucose metabolism and chronic pain. [PDF]

open access: yesCell Biosci
Ma L   +5 more
europepmc   +1 more source

Interstitial N‐Strengthened Copper‐Based Bioactive Conductive Dressings Combined with Electromagnetic Fields for Enhanced Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study developed a nitrogen‐strengthened copper‐iron‐zinc (N‐CuFeZn) alloy bioactive dressing integrated with electromagnetic stimulation. The coaxial dressing, made from 0.04 mm filaments with 1120 MPa tensile strength, showed that electromagnetic activation enhanced therapeutic outcomes by increasing VEGF expression, promoting angiogenesis (2.1 ...
Xiaohui Qiu   +9 more
wiley   +1 more source

Effects of ipriflavone (TC-80, an anti-osteoporotic drug) on acute and chronic pain.

open access: bronze, 1986
Seiji Kuzuna   +5 more
openalex   +2 more sources

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani   +4 more
wiley   +1 more source

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