Results 81 to 90 of about 1,745,006 (315)
Assessment of chronic postsurgical pain after knee replacement : a systematic review [PDF]
, 2013 Objective: Approximately 20% of patients experience chronic pain after total knee replacement (TKR), yet there is no consensus about how best to assess such pain.
Bellamy N +5 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Evaluation of back education programme at the Medical Rehabilitation Unit, Palmerston North Hospital : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]
, 1994 Chronic low back pain is a significant health care problem and is frequently one of the most difficult conditions to treat. For the individual, chronic low back pain evolves into a constellation of problems involving psychological and behavioural ...
Williams, Mei Wah
core
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
From acute to chronic pain: tapentadol in the progressive stages of this disease entity [PDF]
, 2017 OBJECTIVE: Chronic pain is now recognized as a neural disease, which results from a maladaptive functional and structural transformation process occurring over time. In its chronic phase, pain is not just a symptom but also a disease entity.
Coluzzi, Flaminia +3 more
core
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
, 2010 What is chronic pain? Chronic pain is pain that lasts longer than three months. The pain can be there all the time or it can come and go. It can happen anywhere in the body. Chronic pain may include everyday activities such as working, socializing, and caring for self or others.This can lead to depression, anxiety, and trouble sleeping, which can make ...
openaire +1 more source
Altered Excitability and Local Connectivity of mPFC-PAG Neurons in a Mouse Model of Neuropathic Pain [PDF]
, 2018 The medial prefrontal cortex (mPFC) plays a major role in both sensory and affective aspects of pain. There is extensive evidence that chronic pain produces functional changes within the mPFC.
Cheriyan, John, Sheets, Patrick L.
core +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Postsurgical Chronic Pain [PDF]
American Journal of Hospice and Palliative Medicine®, 2010 Any operation, indeed, any surgical intervention inevitably causes acute pain that usually subsides over time. However, persistent, chronic postsurgical pain may be severe in 2% to 10% of patients. As reviewed by Kehlet et al, this discomfort generally lasts longer than 3 to 6 months after surgery.
openaire +3 more sources