Dasatinib and quercetin prevent alveolar bone loss in aged mice
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli +7 more
wiley +1 more source
Effect of propolis extract and chlorhexidine in treating chronic periodontitis: A randomized controlled trial. [PDF]
Shivatare DD +5 more
europepmc +1 more source
Aging and periodontitis increase brain dissemination of oral bacteria
Abstract Background The microbiome is a dynamic system that changes throughout life. Studies have revealed the relationship between periodontal disease and the oral microbiota; however, the impact of periodontal disease on the expression of senescence markers and on the inflammaging of the oral and systemic microbiome remains unclear.
Ozge Unlu +7 more
wiley +1 more source
Comparative evaluation of open flap debridement with or without injectable platelet-rich fibrin in chronic periodontitis treatment. [PDF]
Verma S +6 more
europepmc +1 more source
Abstract Background Periodontal disease (PD) is associated with type 2 diabetes mellitus (T2DM), while periodontal treatment (PT) improves glycemic control in T2DM patients. Leptin and adiponectin belong to the adipokines family and have almost antagonistic functions in inflammatory processes and insulin sensitivity modulation.
Natalia Christaki +3 more
wiley +1 more source
Association of chronic periodontitis in a broad spectrum of cardiometabolic syndrome: A minireview. [PDF]
Gupta S, Lal N, Pradhan A, Verma AK.
europepmc +1 more source
Abstract Background The objective of this systematic review is to evaluate whether periodontitis is associated with impaired oral health–related quality of life (OHRQoL) in adults with systemic conditions. Methods Five databases were searched to identify observational studies that tested the association between periodontitis (diagnosed by clinical ...
Rafael Vargas Bortolaso +5 more
wiley +1 more source
Significance of IL-8 and HMGB1 expression in peripheral blood and gingival sulcus fluid of patients with chronic periodontitis. [PDF]
Liu P, Chen J, Guo X, Wu B.
europepmc +1 more source
Periodontitis during pregnancy: The effect on the gut microbiome and intestinal inflammation
Abstract Background Periodontitis has been epidemiologically associated with adverse pregnancy outcomes, but causality remains difficult to establish in humans due to confounding factors. This study uses a controlled murine model to examine the effects of experimentally induced periodontitis on the composition of the gut microbiota and gastrointestinal
Richard Bright +9 more
wiley +1 more source
Modeling chronic periodontitis in rats: Persistent alveolar bone loss mediated by periodontal pathogens. [PDF]
Skrypnyk M +4 more
europepmc +1 more source

