Results 31 to 40 of about 42,623 (267)

IL‐7R‐Enriched Extracellular Vesicles From the Thymus Drive Colitis via Promoting Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao, Yuheng Liu, Ruibing Yang, Zifeng Zhu, Junwei Wu, Dinghao Li, Jin Su, Yingxin He, Shiqi Luo, Feiyang Cao, Haiyi Deng, Lanmengxi Yang, Ling Zhong, Peiying Peng, Xinyi Wu, Chunmei Cai, Zhen Li, Yujin Wu, Shuofeng Zhu, Jie Wei, Yi Yang, Lifu Wang   +21 more
wiley   +1 more source

The evaluation of mandibular bone density in chronic periodontitis models

Dental Journal, 2018
Background: Bone density, an important factor in functional bone quality, can affect the success of implant osteointegration or orthodontic treatment.
Yuliana Mahdiyah Da’at Arina, F. Ferdiansyah, Mohamad Rubianto   +2 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

The association of aggressive and chronic periodontitis with systemic manifestations and dental anomalies in a jordanian population: a case control study

Head & Face Medicine, 2010
Background The relationship between dental anomalies and periodontitis has not been documented by earlier studies. Although psychological factors have been implicated in the etiopathogenesis of periodontitis, very little information has so far been ...
Karasneh Jumana A, Abbadi Muna S, Taha Anas H, Ababneh Khansa T, Khader Yousef S   +4 more
doaj   +1 more source

Chronic Periodontitis and Erectile Dysfunction

The Journal of Sexual Medicine, 2013
We read the article by Oguz et al. [1] with great interest. The cited study is an interesting contribution to the literature. The relationship between erectile dysfunction (ED) and periodontal disease is explored. The cited authors conclude that an association exists between clinical periodontal parameters and ED. Further, they suggest that periodontal
Bodakci, Mehmet Nuri, Hatipoglu, Namik Kemal, ÖZBEY, İsa   +2 more
openaire   +4 more sources

An Efficient Detection Platform Based on Mesoporous Au@Cr2O3 Particles with Schwarz P Surface for Precise Periodontitis Metabolite Profiling

Advanced Science, EarlyView.
A non‐invasive periodontitis diagnosis platform was developed using Au nanoparticles‐decorated mesoporous Cr2O3 (Au@mCr2O3) particles with Schwarz P surface as matrix for saliva metabolic fingerprinting (SMFs) analysis via MALDI‐MS. With the assistance of machine learning of SMFs, this platform enables efficient diagnosis and the screening of potential
Yue Sun, Yan Wang, Fangying Shi, Wenhe Xie, Yiding Zhang, Heyuhan Zhang, Chunhui Deng, Limin Wu, Meihua Chen, Yonghui Deng   +9 more
wiley   +1 more source

Galectin-3 as a possible link between periodontitis and chronic kidney disease: a cross-sectional study [PDF]

Journal of Yeungnam Medical Science
Background Chronic periodontitis is associated with various systemic inflammatory diseases; however, research on its association with chronic kidney disease (CKD) is relatively limited.
Sri Vidhya Marimuthu, Devi Arul, Muthukumar Santhanakrishnan, Ramprasad Elumalai, Sandhya Suresh, Sathya Selvarajan, Ravindranath Dhulipalla, Ramanarayana Boyapati   +7 more
doaj   +1 more source

Mean Platelet Volume and Salivary C-Reactive Protein Levels among Smokers with Chronic Periodontitis: A Pilot Study [PDF]

Journal of Clinical and Diagnostic Research, 2020
Introduction: Periodontitis is a chronic inflammatory disease with smoking as a major risk factor. Previous studies have shown that elevated number of platelets, platelet activation and Mean Platelet Volume (MPV) are the important indicator of platelet ...
Kunchok J Dolma, Sheela Kumar Gujjari, Jayashree Krishnamurthy, Prashant M Vishwanath   +3 more
doaj   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

MiR‐146a‐5p Suppresses M1 Polarization of Tumor‐Associated Macrophages via IRAK1/NF‐κB Signaling in Colorectal Polyps

Annals of Gastroenterological Surgery, EarlyView.
MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song, Lianhui Wu, Huabin Qiu, Lei Luo, Jianzhao Qiu, Shuping Xiao, Jincai He   +6 more
wiley   +1 more source