Results 141 to 150 of about 9,115 (202)

Persistent Corneal Defect in Chronic Progressive External Ophthalmoplegia

Journal of Medical Optometry, 2023
This unique case highlights the difficulties of managing both CPEO and the complications related to the ocular surface and adnexa, including...
John Conto, Jane Bachman Groth
semanticscholar   +1 more source

Pearls and Oy-sters: Chronic Progressive External Ophthalmoplegia With Electrical Myotonia and Negative Initial Genetic Testing.

Neurology
Chronic progressive external ophthalmoplegia (CPEO), a genetic syndrome characterized by slowly progressive paresis of extraocular muscles, is often due to single large-scale deletions of the mitochondrial genome (mtDNA).
Brian Y Li, Julia H Greenberg, Connolly G Steigerwald, Renkui Bai, K. Tanji, Elina Zakin, Nicolas J. Abreu   +6 more
semanticscholar   +1 more source

Müller Muscle-Conjunctival Resection With Tarsectomy in Chronic Progressive External Ophthalmoplegia.

The Journal of craniofacial surgery (Print)
This report presents 2 cases of chronic progressive external ophthalmoplegia (CPEO) with progressive bilateral ptosis, managed successfully using Müller muscle-conjunctival resection with tarsectomy (MMCRT).
M. Mangan, Emirhan Ozkul, C. Arıcı, Seda Mazmanoglu Atilman   +3 more
semanticscholar   +1 more source

Chronic Progressive External Ophthalmoplegia

Archives of Ophthalmology, 1969
The syndrome of chronic progressive external ophthalmoplegia has been generally regarded as denoting an ocular myopathy. Recent evidence is presented, however, which both denies the universality of a myopathic etiology and demonstrates our present inability to distinguish between myopathy and neural weakness of ocular muscles.
openaire   +2 more sources

Surgical management of ptosis in chronic progressive external ophthalmoplegia

European Journal of Ophthalmology, 2020
Purpose: To determine possible complications and efficacy of ptosis surgery in a series of chronic progressive external ophthalmoplegia (CPEO) patients with healthy tear film.
M. Eshaghi, A. Arabi, Sarvin Eshaghi
semanticscholar   +1 more source

Chronic Progressive External Ophthalmoplegia due to a Rare de novo m.12334G>A MT-TL2 Mitochondrial DNA Variant

Journal of Neuromuscular Diseases, 2020
We describe a patient with chronic progressive external ophthalmoplegia (CPEO) due to a rare mitochondrial genetic variant. Muscle biopsy revealed numerous cytochrome c oxidase (COX)-deficient fibres, prompting sequencing of the entire mitochondrial ...
L. O'Donnell, E. Blakely, K. Baty, M. Alexander, P. Bogdanova-Mihaylova, J. Craig, R. Walsh, F. Brett, Robert W. Taylor, S. Murphy   +9 more
semanticscholar   +1 more source

Severe Chronic Progressive External Ophthalmoplegia-Associated Ptosis Successfully Treated With Scleral Lenses.

Journal of neuro-ophthalmology, 2020
C hronic progressive external ophthalmoplegia (CPEO) is a progressive neuromyopathic disorder marked by bilateral weakness of the levator and extraocular muscles, resulting in blepharoptosis and impaired ocular motility (1,2).
Christina Cherny, Suzanne W. Sherman, Lora R. Dagi Glass   +2 more
semanticscholar   +1 more source

Update on Chronic Progressive External Ophthalmoplegia

Strabismus, 2005
Mitochondrial encephalomyopathies are clinically and genetically heterogeneous disorders. External ophthalmoplegia is the most frequent symptom. Other frequently involved tissues and organs include the retina, heart, limb muscles, peripheral and central nervous system, inner ear and endocrine system.
Viktoria, Bau, Stephan, Zierz
openaire   +2 more sources

Chronic Progressive External Ophthalmoplegia

American Orthoptic Journal, 2005
IntroductionCredit for the first description in the literature regarding chronic progressive external ophthalmoplegia is generally attributed to von Graefe in 1868. Chronic progressive external ophthalmoplegia (CPEO) is a disorder that leads to complete immobility of the eyes.
openaire   +1 more source

Chronic progressive external ophthalmoplegia.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1998
Two cases of chronic progressive external ophthalmoplegia were described. Both of them presented with progressive bilateral ptosis and gradual impairment of ocular mobility. One of the patients had abnormal cerebrospinal fluid protein level. Another patient had muscle biopsy which was compatible with mitochondrial myopathy.
K, Phanthumchinda, S, Sinswaiwong, S, Jonpiputvanich   +2 more
openaire   +1 more source