Results 101 to 110 of about 1,712,061 (282)
Somatic and psychiatric comorbidity in patients with chronic pruritus.
, 2010 It has been reported that 10-50% of patients with pruritus but no skin rash have an underlying systemic disease and up to 70% a psychiatric one. The aim of this retrospective study was to review the records of a large number of patients with chronic ...
Sterner, Magnus +5 more
core +1 more source
Ondansetron Treatment in a Child Presenting with Chronic Intractable Pruritus [PDF]
, 2006 The case of a seven-year-old boy with chronic pruritus secondary to a giant congenital melanocytic nevus is presented. The pruritus did not respond to conventional antipruritic drug treatment, but responded to ondansetron, a selective antagonist of 5 ...
Chantal Frigon, Joëlle Desparmet
core +1 more source
iNew Medicine, EarlyView.ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang +13 more
wiley +1 more source
Myeloid sarcoma presenting as an isolated pancreatic mass in a 3‐year‐old child
JPGN Reports, EarlyView.Abstract Myeloid sarcoma (MS) is an extramedullary tumor of myeloid precursor cells, frequently associated with acute myeloid leukemia (AML), and rarely occurring in isolation. We present a child with obstructive jaundice secondary to a pancreatic head mass.
Jappmann Kaur Monga +7 more
wiley +1 more source
A hepatic enigma: Pediatric presentation of primary biliary cholangitis
JPGN Reports, EarlyView.Abstract Primary biliary cholangitis (PBC) is a chronic autoimmune condition characterized by destruction of intrahepatic bile ducts, leading to fibrosis and cirrhosis of the liver. It is an extremely rare pediatric disease with very few pediatric cases reported to date. Here, we report the case of a 14‐year‐old female who presented with elevated liver
Sindhura Kasturi +3 more
wiley +1 more source
Autonomic and sensory nerve dysfunction in primary biliary cirrhosis [PDF]
, 2004 AIM: Cardiovascular autonomic and peripheral sensory neuropathy is a known complication of chronic alcoholic and non-alcoholic liver diseases. We aimed to assess the prevalence and risk factors for peripheral sensory nerve and autonomic dysfunction using
Horváth, Andrea +8 more
core +1 more source
Dermatology and TherapyIntroduction Chronic inflammatory skin conditions significantly impact the quality of life (QoL) of those affected. Itch is a cardinal symptom in many of these conditions, contributing decisively to the burden of disease.
Manuel P. Pereira +6 more
doaj +1 more source
Patient Needs and Treatment Goals in Chronic Atopic Pruritus: Does Eczema Make a Difference?
Acta Dermato-VenereologicaChronic pruritus (≥ 6 weeks) is a frequent symptom in atopic diseases, with phenotypes ranging from non-lesional skin to inflammatory diseases like atopic dermatitis. Data on patients’ needs and treatment goals depending on the skin phenotype and disease
Svenja Müller +19 more
doaj +1 more source
The Brazilian Alagille syndrome study: New insights from a multicenter national cohort
JPGN Reports, EarlyView.Abstract Objectives To elucidate the natural history of liver disease and identify the predictors of native liver survival (NLS) in a Brazilian cohort of children with Alagille syndrome (ALGS). Methods Multicenter retrospective cohort study of children with ALGS. Descriptive statistics summarized clinical data.
Elisa Carvalho +34 more
wiley +1 more source
JPGN Reports, EarlyView.Abstract Progressive Familial Intrahepatic Cholestasis type 1 (PFIC1) is a multisystem disorder. Although liver transplant (LT) resolves the hepatic disease, post‐LT complications may occur, including severe enteropathy and graft steatosis caused by impaired bile acids handling by the native intestine.
Teresa Botelho +6 more
wiley +1 more source