Results 181 to 190 of about 47,991 (257)

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber, Szabina Horváth, Balázs Zoltán Zsidó, Viktória Kormos, János Konkoly, Csaba Hetényi, Erika Pintér, Ágnes Kemény, Rolland Gyulai   +8 more
wiley   +1 more source

Association of Liver Disease and Chronic Pruritus: A Case-Control Study. [PDF]

Liver Int
Andrade LF, Haq Z, Abdi P, Diaz MJ, Levy C, Yosipovitch G.   +5 more
europepmc   +1 more source

Rebound Pruritus and Urticaria After Discontinuation of Chronic Antihistamine Use—A Scoping Review

Clinical &Experimental Allergy, EarlyView.
Rebound pruritus and urticaria have been reported after discontinuation of chronic cetirizine or levocetirizine use only. Symptoms typically occur within 0.5–5 days after stopping therapy and appear more frequently reported in female patients. Re‐initiation of antihistamines is the most commonly effective management strategy, highlighting the need for ...
Jun Jie Benjamin Seng, Prawira Oka, Ngiap Chuan Tan   +2 more
wiley   +1 more source

Chronic Pruritus in Geriatric Patients: Prevalence, Associated Factors, and Itch-related Quality of Life. [PDF]

Acta Derm Venereol
Günther M, Kobus C, Perner C, Schönenberg A, Prell T.   +4 more
europepmc   +1 more source

Sustained Clinical Improvement in Birch Pollen Allergy After Two Pre‐Seasonal Short Courses of Allergen‐Specific Immunotherapy: A Long‐Term Open‐Label Extension Study

Clinical &Experimental Allergy, EarlyView.
3 years follow‐up study to a DBPC dose‐finding trial investigating subcutaneous immunotherapy with T502 in birch‐pollen induced allergic rhinoconjunctivitis. 154 birch‐pollen allergic adults received short‐course treatment of 10,000 mTU/mL of T502 for 2 years and were observed during the next season without treatment.
Ralph Mösges, Friederike Hüffmeier, Ludger Klimek, Oliver Pfaar, Christian Neuhof, Anna Rybachuk, Cengizhan Acikel, Hacer Sahin, Silke Allekotte, Sandra del Pozo, José Luis Subiza, Miguel Casanovas, Mandy Cuevas, Laura Day, Lea Radtke, Esther Raskopf   +15 more
wiley   +1 more source

Updated Meta-Analysis on Vitamin Supplementation for Chronic Pruritus: Expanding Evidence Beyond Vitamin D. [PDF]

Int J Mol Sci
Kuo WH, Chang KS, Chang MH, Hsiao Y, Tsai RY.   +4 more
europepmc   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

The Relationship Between Chronic Pruritus, Attention-Deficit/Hyperactivity Disorder, and Skin Picking-A Case Series and Narrative Review. [PDF]

J Clin Med
Loos E, Sekar S, Rosin C, Navarini AA, Schwale C, Schaefert R, Müller S.   +6 more
europepmc   +1 more source

Epidemiological, Clinical and Allergic Profile of Patients With Dyshidrotic Eczema (Acute and Recurrent Vesicular Dermatitis): Evaluation of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy (REIDAC)

Contact Dermatitis, EarlyView.
In this exploratory analysis, dyshidrotic eczema demonstrated a distinct sensitisation pattern compared with non‐dyshidrotic hand eczema. The lower proportion of clinically relevant reactions amongst positive patch tests suggests a multi‐factorial and not exclusively allergic background.
Araceli Sánchez‐Gilo, Enrique Gómez de la Fuente, Ana M. Giménez‐Arnau, Juan Francisco Silvestre‐Salvador, Pedro Mercader‐García, Tatiana Sanz‐Sánchez, Violeta Zaragoza‐Ninet, Susana Córdoba‐Guijarro, Javier Miquel‐Miquel, Ricardo González‐Pérez, Inmaculada Ruiz‐Gonzalez, Esther Serra‐Baldrich, José Manuel Carrascosa‐Carrillo, Francisco Javier Ortiz de Frutos, Mercedes Rodríguez‐Serna, María Elena Gatica‐Ortega, Carmen Paredes‐Suárez, Francisco J. Navarro‐Triviño, Pablo Chicharro, María Antonia Pastor‐Nieto, Marta Andreu Barasoain, José‐Juan Pereyra‐Rodríguez, Gemma Melé‐Ninot, Paloma Sánchez‐Pedreño Guillén, Marta Elosua‐González, Miguel Ángel Descalzo, Ignacio García‐Doval, Raquel Barba‐Martín, Leopoldo Borrego   +28 more
wiley   +1 more source

European Society of Contact Dermatitis Guideline for Diagnostic Patch Testing—Recommendations on Best Practice (Update 2026)

Contact Dermatitis, EarlyView.
ABSTRACT The present guideline updates the initial ESCD patch testing guideline, summarizing all aspects of patch testing for the diagnosis of contact allergy in patients suspected of suffering, or having been suffering, from allergic contact dermatitis or other delayed‐type hypersensitivity skin and mucosal conditions. Sections with brief descriptions
Wolfgang Uter, Olivier Aerts, Tove Agner, Richard Brans, Magnus Bruze, Alicia Cannavó, Marie‐Noёlle Crépy, Ana M. Giménez‐Arnau, Margarida Gonçalo, An Goossens, Swen M. John, Carola Lidén, Suzana Ljubojević Hadžavdić, Vera Mahler, Mihaly Matura, Esen Özkaya, Maria Pesonen, Nadia Raison‐Peyron, Thomas Rustemeyer, Radoslaw Spiewak, Luca Stingeni, Ian R. White, S. Mark Wilkinson, Jeanne Duus Johansen   +23 more
wiley   +1 more source