Results 181 to 190 of about 1,712,061 (282)

XOmiVAE-Inspired Transcriptomic Analysis of Chronic Pruritus of Unknown Origin: A Cutaneous State Distinct from Healthy Skin but Not Robustly Separable from Atopic Dermatitis. [PDF]

Biomedicines
Zou YM, Wu MN, Zhou DM, Jiang WB, Bai YP.   +4 more
europepmc   +1 more source

Knowledge, Attitudes, and Practices of Dermatologists on Chronic Pruritus and Its Management. [PDF]

Cureus
Talwar A, Shivhare S, Joshi DK, Gala M, Muchhala SS, Bhagat SV, Sanghavi A, Katare S, Kotak BP.   +8 more
europepmc   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source

Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures

Allergy, EarlyView.
This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally, Takeshi Yoshida, Shan Gao, Xueya Cai, Donald Y. M. Leung, Lisa A. Beck, Anna De Benedetto   +6 more
wiley   +1 more source

The effect of medication use on chronic pruritus in patients with type 2 diabetes mellitus: a multicenter cross-sectional study. [PDF]

Sci Rep
Xu M, Gao X, Liu Z, Zhang L, Wang Z, Zhuang H, Fu W, Yao S, Zhang L, Zhou S, Liu J.   +10 more
europepmc   +1 more source

Effect of Abrocitinib on the Skin Microbiome in Patients With Moderate‐to‐Severe Atopic Dermatitis

Allergy, EarlyView.
Atopic dermatitis (AD) is characterized by microbial dysbiosis. This study aimed to evaluate the effects of abrocitinib, a JAK1‐selective inhibitor, on the skin microbiome and its potential associations with clinical outcomes in patients with AD. Abrocitinib treatment was associated with increased skin microbial diversity and decreased Staphylococcus ...
Madeline Kim, Ester Del Duca, Joel Correa Da Rosa, Juliana Pulsinelli, Yeriel Estrada, Dan Xu, Gary Chan, Allshine Chen, Erman Güler, Karen Page, Emma Guttman‐Yassky   +10 more
wiley   +1 more source

Chronic cough and chronic pruritus in older adults: a population-based cross-sectional study. [PDF]

ERJ Open Res
Bollemeijer JF, Riemann S, Thio HB, Nijsten TEC, Brusselle G, Pardo LM.   +5 more
europepmc   +1 more source

EADV Task Force Pruritus White Paper on chronic pruritus and chronic prurigo

Chronic pruritus (CP) is frequent in general medicine and the most common complaint in general dermatology. The prevalence of CP is expected to rise in the future due to the ageing population. The clinical presentation, underlying aetiology and treatment strategy of CP are heterogeneous.
Ständer, Sonja||, Pereira, Manuel Pedro||, Zeidler, Claudia||, Legat, Franz Josef||, Misery, Laurent||, Lönndahl, Louise||, Bewley, Anthony||, Brenaut, Emilie||, Bobko, Svetlana||, Elberling, Jesper||, Evers, Andrea W. M.||, Garcovich, Simone||, Gieler, Uwe||, Gonçalo, Margarida||, Kupfer, Joerg||, Lambert, Julien||, Lvov, Andrey||, Metz, Martin||, Michenko, Anna||, Papadavid, Evangelia||, Reich, Adam||, Savk, Ekin||, Schneider, Gundrun||, Schut, Christina||, Serra-Baldrich, E||, Ständer, Hartmut F.||, Szepietowski, Jacek C||, Wallengren, Joanna||, Weisshaar, Elke||, Augustin, Matthias||   +29 more
openaire   +1 more source

Influence of Environmental Pollution on Basophil Reactivity to Birch Pollen Allergens in Atopic and Non‐Atopic Subjects

Allergy, EarlyView.
Birch pollen and PM10 are key determinants of clinical symptoms, particularly in asthma. Allergic people react stronger to the pollen collected in the highly polluted area than in the less polluted areas. When evaluating the effectiveness of allergen immunotherapy, it is essential to consider not only pollen concentrations but also levels of air ...
Maria Czarnobilska, Małgorzata Bulanda, Ewa Czarnobilska, Wojciech Dyga, Marek Jutel, Dorota Myszkowska   +5 more
wiley   +1 more source

Chronic Pruritus Severity and Its Association with Clinical Frailty in Geriatric Dermatology Patients: A Cross-Sectional Study. [PDF]

J Clin Med
Kurmuş GI, Menteşoğlu D, Çöteli S, Kartal SP.   +3 more
europepmc   +1 more source