Results 121 to 130 of about 1,166,644 (417)
Advanced Science, EarlyView.Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang +8 more
wiley +1 more source
Chronic renal failure in patients hospitalized for heart failure
Cardiologia HungaricaAim of the study: Assessment of the incidence of real and diagnosed chronic renal failure in patients hospitalized for heart failure, assessment of factors affecting the recording of the diagnosis.
Tomcsányi János +3 more
doaj +1 more source
Sparse Longitudinal Representations of Electronic Health Record Data for the Early Detection of Chronic Kidney Disease in Diabetic Patients [PDF]
arXiv, 2020 Chronic kidney disease (CKD) is a gradual loss of renal function over time, and it increases the risk of mortality, decreased quality of life, as well as serious complications. The prevalence of CKD has been increasing in the last couple of decades, which is partly due to the increased prevalence of diabetes and hypertension.
arxiv
Nonrecovery of kidney function and death after acute on chronic renal failure.
American Society of Nephrology. Clinical Journal, 2009 BACKGROUND AND OBJECTIVES Relatively little is known about clinical outcomes, especially long-term outcomes, among patients who have chronic kidney disease (CKD) and experience superimposed acute renal failure (ARF; acute on chronic renal failure ...
Chi-yuan Hsu +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo +20 more
wiley +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Advanced Science, EarlyView.Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu +17 more
wiley +1 more source
The relationship between chronic kidney disease and cancer [PDF]
Journal of Nephropathology, 2018 Seyed Majid Mousavi Movahhed +6 more
doaj +1 more source
Cisplatin Induced Nephrotoxicity
مجله دانشگاه علوم پزشکی بیرجند, 2014 Cisplatin is a potent chemotherapy agent which is used to treat a broad spectrum of solid cancers. However, its clinical use is limited due to its nephrotoxicity with a decline in the glomerular filtration rate that occur in 15-30% of patients.
Seyed Seifollah Beladi Mousavi +1 more
doaj
Towards Quantification of Bias in Machine Learning for Healthcare: A Case Study of Renal Failure Prediction [PDF]
arXiv, 2019 As machine learning (ML) models, trained on real-world datasets, become common practice, it is critical to measure and quantify their potential biases. In this paper, we focus on renal failure and compare a commonly used traditional risk score, Tangri, with a more powerful machine learning model, which has access to a larger variable set and trained on
arxiv
THE NATURE OF THE RENAL CIRCULATORY CHANGES IN CHRONIC CONGESTIVE FAILURE AS REFLECTED BY RENAL TUBULAR MAXIMAL FUNCTIONS 12 [PDF]
, 1950 Jacob Grossman +3 more
openalex +1 more source