Results 131 to 140 of about 1,128,531 (391)

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

open access: yesAdvanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan   +12 more
wiley   +1 more source

Urocystitis, pyelonephritis, renal papillary necrosis and chronic tubulointerstitial disease causing chronic renal insufficiency in a Siberian tiger (Panthera tigris altaica): a case report

open access: yesVeterinární Medicína, 2018
The present case report describes a case of chronic renal failure characterised by renal medullary fibrosis and renal papillary necrosis in a male Siberian tiger (Panthera tigris altaica).
S.W. Lee   +7 more
doaj   +1 more source

kurz und kn@pp news : Nr. 11 [engl. Fassung] [PDF]

open access: yes, 2008
* Prize for excellent teaching * Drug prescription safety and renal failure * Prof. Gerlach on the Health Research Council of the German Ministry for Education and Research * Health in Old Age * DEGAM against IGeLn * A Meeting of

core  

Determining Some Biochemical Parameters and Screening for Hepatitis B and C in Patients with Chronic Kidney Disease in Tikrit City [PDF]

open access: yes
Chronic renal failure is a life-threatening disease. This study aimed to examine some biochemical and hematological variables and liver C virus B and C in renal failure patients undergoing hemodialysis and compare these results with healthy individuals ...
Abdulrahman, Noura B.   +2 more
core   +2 more sources

Engineering the Immune Response to Biomaterials

open access: yesAdvanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam   +12 more
wiley   +1 more source

The relationship between chronic kidney disease and cancer [PDF]

open access: yesJournal of Nephropathology, 2018
Seyed Majid Mousavi Movahhed   +6 more
doaj   +1 more source

Cisplatin Induced Nephrotoxicity

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2014
Cisplatin is a potent chemotherapy agent which is used to treat a broad spectrum of solid cancers. However, its clinical use is limited due to its nephrotoxicity with a decline in the glomerular filtration rate that occur in 15-30% of patients.
Seyed Seifollah Beladi Mousavi   +1 more
doaj  

Mechanisms and Therapeutic Strategies for Minority Cell‐Induced Paclitaxel Resistance and Tumor Progression Mediated by Mechanical Forces

open access: yesAdvanced Science, EarlyView.
This study provides new perspectives into the interactions between mechanical forces and cellular dynamics within the tumor microenvironment, particularly elucidating how minority Paclitaxel‐resistant cancer cells (MRCs) promote tumor progression and treatment resistance through mechanical forces and also providing effective treatment strategies for ...
Xueyan Feng   +12 more
wiley   +1 more source

STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy