Results 141 to 150 of about 672,182 (355)

164: Plasma-HGH, -TSH and -cortisol in children with chronic renal failure (CRF) [PDF]

open access: bronze, 1976
M Klett   +4 more
openalex   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

open access: yesAdvanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich   +8 more
wiley   +1 more source

Hubungan Dukungan Keluarga dengan Kecemasan Pasien Gagal Ginjal Kronik di Ruang Hemodialisa Rumah Sakit Royal Prima Medan [PDF]

open access: yes, 2019
Patients with chronic renal failure who undergo hemodialysis often experience a decrease in physical activity and this decrease affects the anxiety condition. The family support may decrease anxiety in patients undergoing hemodialysis therapy.
Anggeria, E. (Elis)
core   +1 more source

Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition

open access: yesAdvanced Science, EarlyView.
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu   +12 more
wiley   +1 more source

Preliminary approach to cardiorenal syndrome in dogs affected by chronic mitral valve disease [PDF]

open access: yes, 2015
In human medicine, primary disorders of the heart often result in secondary dysfunction or injury to the kidneys. The coexistence of the two problems in the same patient is referred as cardiorenal syndrome (CRS).
Martinelli, Elisa
core  

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

open access: yesAdvanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang   +8 more
wiley   +1 more source

Перитонеальный диализ как метод заместительной почечной терапии в популяции больных хроническими болезнями почек [PDF]

open access: yes, 2007
Представлен регистр больных с хроническими болезнями почек в Харьковской области. Освещены вопросы ранней диагностики хронической почечной недостаточности, указаны методы заместительной почечной терапии, особенности постоянного амбулаторного ...
Андоньева, Н.М.   +1 more
core  

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

open access: yesAdvanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai   +5 more
wiley   +1 more source

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