Results 141 to 150 of about 1,166,644 (417)

EGFR‐TKIs Induced DPP4 Drives Metabolic Reprogramming of Persister Cells in Lung Cancer

Advanced Science, EarlyView.
Drug‐tolerant persister (DTP) cells emerge early during EGFR‐TKI treatment, preceding the development of acquired resistance. Elevated DPP4 in DTP cells drives metabolic reprogramming and antioxidant adaptation, promoting cell survival under drug pressure.
Yuanzhou Zhang, Xiaojun Zhang, Xupeng Yang, Xingshi Chen, Yuehong Wang, Jingying Hu, Rui Liu, Xiaoying Luo   +7 more
wiley   +1 more source

Adaptive Local Binary Pattern: A Novel Feature Descriptor for Enhanced Analysis of Kidney Abnormalities in CT Scan Images using ensemble based Machine Learning Approach [PDF]

arXiv
The shortage of nephrologists and the growing public health concern over renal failure have spurred the demand for AI systems capable of autonomously detecting kidney abnormalities. Renal failure, marked by a gradual decline in kidney function, can result from factors like cysts, stones, and tumors.
arxiv  

Psychological aspects of the management of chronic renal failure. [PDF]

, 1968
W. A. Cramond, P. R. Knight, J. R. Lawrence, Bruce Higgins, J. H. Court, F. M. MacNamara, A. R. Clarkson, Chloe Miller   +7 more
openalex   +1 more source

CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade

Advanced Science, EarlyView.
This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou, Wenli Zhao, Yihan Zhu, Hongyan Liu, Yicheng Sun, Zhengrong Gong, Xuanyi Li, Ziying Liu, Kang Wen, Yicheng Wang, Jie Ren, Ruipei Xiao, Ling Jiang, Yanfeng Hu, Enguang Bi, Xiaoyong Zhang   +15 more
wiley   +1 more source

Перитонеальный диализ в структуре специализированной нефрологической помощи [PDF]

, 2006
Показаны возможности специализированной нефрологической помощи больным хроническими болезнями почек в стадии хронической почечной недостаточности. Охарактеризован постоянный амбулаторный перитонеальный диализ как современный метод заместительной почечной
Андоньева, Н.М., Лесовой, В.Н.   +1 more
core  

International Comparison of Geriatric‐Associated Variables in Major Gastroenterological Surgery Between National Clinical Database and American College of Surgeons National Surgical Quality Improvement Program

Annals of Gastroenterological Surgery, EarlyView.
Geriatric surgical risk factors and outcomes were compared between the US and Japanese databases. Geriatric‐associated preoperative variables and outcomes similarly increased with age. Mobility and functional domains differed between the two databases. ABSTRACT Backgrounds Incidence of malignant disease in older patients has been increasing.
Yasuhide Kofunato, Xane Peters, Arata Takahashi, Mark E. Cohen, Hiraku Kumamaru, Mitsukazu Gotoh, Yoshihiro Kakeji, Yasuyuki Seto, Yuko Kitagawa, Ken Shirabe, Hideki Ueno, Hiroaki Miyata, Clifford Y. Ko, Shigeru Marubashi   +13 more
wiley   +1 more source

The effect of continuous care model on parents’ knowledge and controlling symptoms and recurrence in children with nephrotic syndrome

Majallah-i Bālīnī-i Parastārī va Māmāyī, 2016
Background and aims: Nephrotic syndrome is the most common manifestation of glomerular damage in children. Due to being a chronic disease as well as the need to continuing the provision cares to reduce the recurrence of disease, this research was aimed ...
Ashrafalsadat Hakim, Ehsan Valavi, Semin Madhushimazraei, Mahmoud Latefi, Bahman Dashtbozorge   +4 more
doaj  

Renal function changes in chronic hepatitis B patients [PDF]

arXiv
The best way to treat chronic hepatitis B is with pegylated interferon alone or with oral antiviral drugs. There is limited research comparing the renal safety of entecavir and tenofovir when used with pegylated interferon. This study will compare changes in renal function in chronic hepatitis B patients treated with pegylated interferon and either ...
arxiv  

Renal function in chronic heart failure : a cohort study [PDF]

, 2014
University of Technology Sydney. Faculty of Health.Renal dysfunction is strongly associated with adverse health outcomes in chronic heart failure. The term cardio-renal syndrome has been proposed to describe the theoretical models developed to explain ...
Sheerin, NJ
core  

Mycosis Fungoides, Sézary Syndrome, and Cutaneous B‐Cell Lymphomas: 2025 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov, Trilokraj Tejasvi, Ryan A. Wilcox   +2 more
wiley   +1 more source