Results 271 to 280 of about 1,128,531 (391)

Atorvastatin, etanercept and the nephrogenic cardiac sympathetic remodeling in chronic renal failure rats. [PDF]

J Geriatr Cardiol
Xu JY, Xue ZK, Zhang YR, Liu X, Zhang X, Yang X, Liu T, Chen KY.   +7 more
europepmc   +1 more source

Relation between serum group II pepsinogen concentration and the degree of Brunner's gland hyperplasia in patients with chronic renal failure. [PDF]

, 1985
H. Paimela, Matti Härkönen, S.‐L. Karonen, L G Tallgren, S Stenman, Jouni Ahonen   +5 more
openalex   +1 more source

The effect of severe renal impairment on the pharmacokinetics, safety and tolerability of balcinrenone

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of this phase 1 trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone (previously AZD9977) in participants with severe renal impairment vs. those with normal renal function. Methods Participants with severe renal impairment (estimated glomerular filtration rate [eGFR] < 30 mL/min/1.73 m2) not on dialysis were ...
Chandrali S. Bhattacharya, Hans Ericsson, Susanne Johansson, Joanna Parkinson, Simina M. Boca, Ye Yang, Maria Heijer, Greggory Housler, Maria Leonsson‐Zachrisson, Judith Hartleib‐Geschwindner, Patricia Ely Pizzato   +10 more
wiley   +1 more source

Variability in intestinal drug metabolizing enzymes and transporters in Crohn's disease and potential impact on oral drug absorption

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia, Brahim Achour, Zubida M. Al‐Majdoub, Amin Rostami‐Hodjegan, Jill Barber   +4 more
wiley   +1 more source

Paracetamol and its metabolites in children and adults with spinal muscular atrophy – a population pharmacokinetic model

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao, Marie Mostue Naume, Brenda C. M. de Winter, Thomas Krag, Sissel Sundell Haslund‐Krog, Karoline Lolk Revsbech, John Vissing, Helle Holst, Morten Hylander Møller, Tessa Munkeboe Hornsyld, Morten Dunø, Christina Engel Hoei‐Hansen, Alfred Peter Born, Per Bo Jensen, Mette Cathrine Ørngreen   +14 more
wiley   +1 more source

Topical Efinaconazole Combined With Drilling and Grinding for Onychomycosis in Chronic Renal Failure Patients: A Pilot Study. [PDF]

Ann Dermatol
Park SH, Jang SH, Ahn SW, Hong SM, Seol JE, Kim H.   +5 more
europepmc   +1 more source

Loss of calcium from axial and appendicular skeleton in patients with chronic renal failure

, 1974
S.H. Cohn, Kenneth J. Ellis, R.C. Caselnova, Syed Asad, Joseph M. Letteri   +4 more
openalex   +2 more sources

Accumulation of aluminium in chronic renal failure due to administration of albumin replacement solutions. [PDF]

, 1986
E.R. Maher, Edwina A. Brown, J R Curtis, M. E. Phillips, Barry Sampson   +4 more
openalex   +1 more source

Potassium deficiency in chronic renal failure.

Kidney International, 1973
Gordon L. Bilbrey, Norman W. Carter, Martin G. White, John F. Schilling, James P. Knochel, Julio Borroto   +5 more
semanticscholar   +1 more source

Anticoagulation intensity and outcomes among southeast‐Asians with moderate‐to‐severe mitral valve stenosis

British Journal of Clinical Pharmacology, EarlyView.
Objective To determine the optimal anticoagulation intensity of warfarin in a South‐East Asian population with moderate‐to‐severe rheumatic mitral stenosis. Methods A multicentre, retrospective study examined patients with rheumatic mitral stenosis who had not undergone valve replacement or repair and required long‐term warfarin therapy at two ...
Punyawee Puchsaka, Wipharak Rattanavipanon, Sararat Phetroong, Rudeekorn Ue‐sethasakdhi, Suparat Wattanasombat, Wattana Wongtheptien, Surakit Nathisuwan   +6 more
wiley   +1 more source