Results 271 to 280 of about 739,236 (344)

Combination of Fushengong decoction with Western medicine on patients with chronic renal failure: An observational study. [PDF]

Medicine (Baltimore)
Zou B, Yuan Q, Luo H, Wang M, Chen X, Gao Z, Wang J, Peng Y, Yang H, Dai F, Huang X.   +10 more
europepmc   +1 more source

BHLHE40 Orchestrates Effector Tissue‐Resident Memory CD8+ T Cells and Limits Long‐Term Survival of Kidney Graft

Advanced Science, EarlyView.
An effector subset of TRM, defined as CD49a+PD1hi CD8+ TRM, represents a BHLHE40‐orchestrated resident immune component that, rather than circulating cells, plays as a major contributor to allograft rejection. ABSTRACT Tissue‐resident memory T cells (TRM), which function against tumors, infections, and non‐self antigens in organ transplantation ...
Junbo Li, Bo Yang, Tianhui Pan, Xi Zhou, Zhibo Ma, Du Tang, Bowen Xie, Jing Liu, Zhishui Chen, Peixiang Lan   +9 more
wiley   +1 more source

Topical Efinaconazole Combined With Drilling and Grinding for Onychomycosis in Chronic Renal Failure Patients: A Pilot Study. [PDF]

Ann Dermatol
Park SH, Jang SH, Ahn SW, Hong SM, Seol JE, Kim H.   +5 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Focus on Mitochondrial Respiratory Chain: Potential Therapeutic Target for Chronic Renal Failure. [PDF]

Int J Mol Sci
Wang Y, Yang J, Zhang Y, Zhou J.
europepmc   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Blood purification therapy in chronic renal failure and its impact on renal index, serological index, and inflammatory factors. [PDF]

Ann Med Surg (Lond)
Butt B, Mushtaq A, Hameed FA, Abbasi MSR, Tariq M, Akbar A, Jadoon SK, Tasneem S, Ahmad M, Zeb A, Alvi S.   +10 more
europepmc   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

The prevalence of onychomycosis in patients with chronic renal failure undergoing dialysis: A cross-sectional study. [PDF]

Heliyon
Eftekhari H, Haghdar Saheli Y, Ashoobi MT, Mahjoob M, Kazemnezhad Leyli E, Bagheri Toolaroud P.   +5 more
europepmc   +1 more source