MORPHOPATHOLOGICAL STUDY ON THE EXTIRPATED KIDNEYS IN DIALYZED PATIENTS WITH CHRONIC RENAL FAILURE
Junzo Nakanishi
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EGFR‐TKIs Induced DPP4 Drives Metabolic Reprogramming of Persister Cells in Lung Cancer
Drug‐tolerant persister (DTP) cells emerge early during EGFR‐TKI treatment, preceding the development of acquired resistance. Elevated DPP4 in DTP cells drives metabolic reprogramming and antioxidant adaptation, promoting cell survival under drug pressure.
Yuanzhou Zhang+7 more
wiley +1 more source
Retracted: Physical Exercise and Patients with Chronic Renal Failure: A Meta-Analysis. [PDF]
International BR.
europepmc +1 more source
AI‐Driven De Novo Design of Ultra Long‐Acting GLP‐1 Receptor Agonists
De novo GLP‐1RAs can be computationally designed to exhibit extended half‐life and superior efficacy compared to Semaglutide. Abstract Peptide drugs have revolutionized modern therapeutics, offering novel treatment avenues for various diseases. Nevertheless, low design efficacy, time consumption, and high cost still hinder peptide drug design and ...
Ting Wei+13 more
wiley +1 more source
Atorvastatin, etanercept and the nephrogenic cardiac sympathetic remodeling in chronic renal failure rats. [PDF]
Xu JY+7 more
europepmc +1 more source
Bioprinted Organoids: An Innovative Engine in Biomedicine
Bioprinted organoids refer to either the printing of stem cells into tissue shape and subsequent differentiate into organoids, or assembling induced organoids as bioinks to replicate native organ. It enables the creation of miniaturized organs with complex architectures and physiological functions, potentially enhancing reproducibility, throughput, and
Zhengwei Li+11 more
wiley +1 more source
Abnormal norepinephrine uptake and release in brain synaptosomes in chronic renal failure
Miroslaw Smogorzewski+2 more
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CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade
This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou+15 more
wiley +1 more source
Topical Efinaconazole Combined With Drilling and Grinding for Onychomycosis in Chronic Renal Failure Patients: A Pilot Study. [PDF]
Park SH+5 more
europepmc +1 more source