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Advanced Science, EarlyView.This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin +16 more
wiley +1 more source
Advanced Science, EarlyView.This study proposes a universal catalytic DNA circuits termed TACTIC (Thermus thermophilus protein‐driven autocatalytic circuit) for one‐pot detection of DNA and RNA in multiple clinical samples. Integrated with machine learning, TACTIC accurately profile the distinct expression of four extracellular vesicle‐derived miRNAs across different samples and ...
Zuowei Xie +12 more
wiley +1 more source
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Journal of Gerontological Nursing, 1987
Older diabetic patients with chronic renal failure are generally unable to meet the standard stringent eligibility criteria established for renal transplant candidates. The nurse must understand the complex physiological processes that occur when the older diabetic patient is being dialyzed.
H M, Plawecki, S, Brewer, J A, Plawecki
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Older diabetic patients with chronic renal failure are generally unable to meet the standard stringent eligibility criteria established for renal transplant candidates. The nurse must understand the complex physiological processes that occur when the older diabetic patient is being dialyzed.
H M, Plawecki, S, Brewer, J A, Plawecki
openaire +2 more sources
Homocysteine and Chronic Renal Failure
Mineral and Electrolyte Metabolism, 1999Homocysteine, a sulfur amino acid, is an important methionine derivative, which has been implicated in the pathogenesis of atherothrombosis. Although only observational, epidemiological studies are available at present, the evidence of an association between hyperhomocysteinemia and increased cardiovascular risk is quite strong and this is confirmed ...
PERNA, Alessandra +4 more
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Renal Osteodystrophy in Chronic Renal Failure
Seminars in Nephrology, 2002Bone disease develops relatively early in the development of chronic renal failure. Much of what is known about the evaluation and management of renal osteodystrophy in chronic renal failure is based on knowledge obtained in the dialysis population. The classic bone lesion found in the dialysis population is osteitis fibrosa, the high turnover lesion ...
L Tammy, Ho, Stuart M, Sprague
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Dopamine in Chronic Renal Failure
American Journal of Hypertension, 1990In patients with renal disease a reduced renal vasodilatory but conserved natriuretic response to dopamine is observed. An inverse relationship exists between baseline renal function and the dopamine-induced changes in effective renal plasma flow and glomerular filtration rate over a wide range of dopamine doses.
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Nutrition in Chronic Renal Failure
The American Journal of Clinical Nutrition, 1956Proper management of the patient with chronic renal failure entails a knowledge of how the normal kidney does its work, common kidney function tests and their differential value, chemical abnormalities in chronic renal failure, and chemical derangements in various types of renal disease. Functions of Normal Kidney The functional unit of the kidney is
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