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Effects of Chronic Renal Failure on Kidney Drug Transporters and Cytochrome P450 in Rats
Drug Metabolism And Disposition, 2011Chronic renal failure (CRF) leads to decreased drug renal clearance due to a reduction in the glomerular filtration rate. However, little is known about how renal failure affects renal metabolism and elimination of drugs.
Judith Naud+7 more
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Dopamine in Chronic Renal Failure
American Journal of Hypertension, 1990In patients with renal disease a reduced renal vasodilatory but conserved natriuretic response to dopamine is observed. An inverse relationship exists between baseline renal function and the dopamine-induced changes in effective renal plasma flow and glomerular filtration rate over a wide range of dopamine doses.
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Nutrition in Chronic Renal Failure
The American Journal of Clinical Nutrition, 1956Proper management of the patient with chronic renal failure entails a knowledge of how the normal kidney does its work, common kidney function tests and their differential value, chemical abnormalities in chronic renal failure, and chemical derangements in various types of renal disease. Functions of Normal Kidney The functional unit of the kidney is
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AJP - Renal Physiology, 2010
Oxidative stress and inflammation are constant features and major mediators of progression of chronic kidney disease (CKD). Nuclear factor erythroid-2-related factor-2 (Nrf2) confers protection against tissue injury by orchestrating antioxidant and ...
H. J. Kim, N. Vaziri
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Oxidative stress and inflammation are constant features and major mediators of progression of chronic kidney disease (CKD). Nuclear factor erythroid-2-related factor-2 (Nrf2) confers protection against tissue injury by orchestrating antioxidant and ...
H. J. Kim, N. Vaziri
semanticscholar +1 more source
Chronic renal failure: a neglected comorbidity of COPD.
Chest, 2010BACKGROUND To the best of our knowledge, the association between COPD and chronic renal failure (CRF) has never been assessed. Lean mass is frequently reduced in COPD, and the glomerular filtration rate (GFR) might be depressed in spite of normal serum ...
R. Incalzi+5 more
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Chronic renal failure in India
Nephrology Dialysis Transplantation, 1993In a series of 2028 patients with chronic renal failure, the diseases leading to renal failure, the presence or absence of reversible factors and their nature, and the rate of decline of renal function of the most common conditions have been described and analysed.
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Endothelin in chronic renal failure
Nephrology Dialysis Transplantation, 1992The aims of the present study were to determine plasma endothelin (ET) in chronically uraemic patients, the renal clearance of endogenous ET in normal dog and man, and the effect of acute volaemic expansion on ET. The mean plasma ET concentration in haemodialysis patients was 57.5 +/- 5 pg/ml before haemodialysis and remained unchanged at 52.5 +/- 5 pg/
F. Masson+7 more
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JAMA: The Journal of the American Medical Association, 1982
Nephrologists may be very proud to have developed excellent techniques for replacing renal function and to have improved renal graft survival to such an extent that the kidney is the only organ for which transplantation is now a routine. Unfortunately, the same cannot be said concerning the conservative management of chronic renal failure (CRF ...
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Nephrologists may be very proud to have developed excellent techniques for replacing renal function and to have improved renal graft survival to such an extent that the kidney is the only organ for which transplantation is now a routine. Unfortunately, the same cannot be said concerning the conservative management of chronic renal failure (CRF ...
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Effects of Gum Arabic in rats with adenine-induced chronic renal failure
Experimental biology and medicine, 2010Gum Arabic (GA [Acacia senegal]) is reputed, in Arabian medicinal practices, to be useful in treating patients with chronic renal failure (CRF), albeit without strong scientific evidence. We have previously shown that GA had no significant effect in rats
B. Ali+7 more
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False renal failure and chronic renal failure [PDF]
False renal failure is an increase in Scr without a fall in GFR due to one of the etiologies listed in Table 7.1. (See the section, Misleading Elevation in Scr, in Chapter 5.) The physician needs to consider this diagnosis when the Scr increases without a change in BUN or when he recognizes one of the conditions on Table 7.1.
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