Urine Neutrophil Gelatinase Associated Lipocalin as a Predictor of Vesicoureteral Reflux and Renal Parenchymal Damage: A Systematic Review [PDF]
Journal of Pediatrics Review, 2023 Background: Vesicoureteral reflux (VUR) is the most common congenital urinary tract abnormality in children. Renal parenchymal damage is the most devastating complication of severe undiagnosed VUR.
Azar Nickavar +2 more
doaj
Arterial stiffening provides sufficient explanation for primary hypertension [PDF]
, 2013 Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity and mortality. Its etiology remains enigmatic despite intense research efforts over many decades.
arxiv +1 more source
Identification and estimation of treatment effects on long-term outcomes in clinical trials with external observational data [PDF]
arXiv, 2022 In biomedical studies, estimating drug effects on chronic diseases requires a long follow-up period, which is difficult to meet in randomized clinical trials (RCTs). The use of a short-term surrogate to replace the long-term outcome for assessing the drug effect relies on stringent assumptions that empirical studies often fail to satisfy.
arxiv
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy.
New England Journal of Medicine, 2019 BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium-glucose cotransporter 2 (SGLT2), exploratory results have ...
V. Perkovic +23 more
semanticscholar +1 more source
Acute kidney injury on chronic kidney disease: From congestive heart failure to light chain deposition disease and cast nephropathy in multiple myeloma [PDF]
, 2019 Acute on chronic renal failure is a common but notably broad diagnosis. We present a 64-year-old man with a history of diastolic heart failure and chronic kidney disease, admitted for an elevated creatinine.
Cheng, Steven +3 more
core +1 more source
Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy [PDF]
, 2014 Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is
Haylor, John, Shrestha, Badri Man
core +3 more sources
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Effect of prednisolone on linear growth in children with nephrotic syndrome
Jornal de Pediatria, 2020 Objective: This study aims at determining the relationship between prednisolone cumulative dose and linear growth in pre-pubertal children with idiopathic nephrotic syndrome.
Ehsan Valavi +4 more
doaj +2 more sources
Segmentation of diagnostic tissue compartments on whole slide images with renal thrombotic microangiopathies (TMAs) [PDF]
arXiv, 2023 The thrombotic microangiopathies (TMAs) manifest in renal biopsy histology with a broad spectrum of acute and chronic findings. Precise diagnostic criteria for a renal biopsy diagnosis of TMA are missing. As a first step towards a machine learning- and computer vision-based analysis of wholes slide images from renal biopsies, we trained a segmentation ...
arxiv
Perbedaanindeks Massa Tubuh (IMT) Pada Pasien Gagal Ginjal Kronik Dengan DM Dan Tanpa DM Yang Menjalani Hemodialisis Rutin Di RSUD Dr. Moewardi [PDF]
, 2018 Chronic kidney disease (CKD) is a disease that leads to progressive kidney function decline, and usually ends with renal failure. The prevalence of CKD in Indonesia is 0.2% and increases with age. DM ranks second as the cause of CKD. Hemodialysis becomes
-, dr. Suryo Aribowo T., M.Kes., Sp.PD (KHOM) +1 more
core