Results 51 to 60 of about 436,308 (258)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Chronic renal failure in patients hospitalized for heart failure

Cardiologia Hungarica
Aim of the study: Assessment of the incidence of real and diagnosed chronic renal failure in patients hospitalized for heart failure, assessment of factors affecting the recording of the diagnosis.
Tomcsányi János, Arányi Péter, Kántor Zita, Csizmadia Zoltán   +3 more
doaj   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

CHRONIC RENAL FAILURE

Health and Society
Objective: to describe the concepts and characteristics, epidemiology of chronic renal failure, causes, clinical manifestations, treatment, pathophysiology and nursing care for patients with chronic renal failure. Materials and methods: the approach of the work was done through a clinical-problem case study.
Michellly Pereira Montenegro, Marlete Scremin, Sylmara Corrêa Monteiro, Kellen Raissa de Souza, Valéria Carvalho Fernandes, Davidson Gonçalves Soares, Weslane Almeida Cavalcanti Magalhães, Joyce Cordeiro de Souza Ferreira, Reginalda Maciel, Sarah Martins Souza, Paulielly Glória dos Santos, Victor Guilherme Pereira, Mônica Prates Queiroz, Diego Barbosa Rocha, Sarah Gabrielle Rodrigues Peixoto   +14 more
openaire   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

Cisplatin Induced Nephrotoxicity

مجله دانشگاه علوم پزشکی بیرجند, 2014
Cisplatin is a potent chemotherapy agent which is used to treat a broad spectrum of solid cancers. However, its clinical use is limited due to its nephrotoxicity with a decline in the glomerular filtration rate that occur in 15-30% of patients.
Seyed Seifollah Beladi Mousavi, Abbas Ali Zeraati   +1 more
doaj  

Contractile responses of urinary bladder in an experimental model of chronic renal failure

Biomolecules & Biomedicine, 2012
Chronic kidney disease is a public health problem with increasing prevalence caused by diabetes, hypertension and glomerulonephritis. Number of publications investigate the lower urinary tract dysfunction due to CKD is limited.
Hüseyin Biçer, Esat Korgali, Gökhan Gökçe, Semih Ayan, Şahin Yıldırım, E. Yener Gültekin   +5 more
doaj   +1 more source

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

Advanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu, Zhiqi Cai, Xiangxin Sun, Hanyi Zhang, Yiming Hao, Jun Wu, Zekun Yan, Xue Wu, Yiqi Liang, Liming Wang, Songnan Qu   +10 more
wiley   +1 more source

The relationship between chronic kidney disease and cancer [PDF]

Journal of Nephropathology, 2018
Seyed Majid Mousavi Movahhed, Seyed Seifollah Beladi Mousavi, Fatemeh Hayati, Shokouh Shayanpour, Shahla Ahmadi Halili, Leila Sabetnia, Zaher Khazaei   +6 more
doaj   +1 more source

Being adolescent with chronic renal failure: a view through existential phenomenology

Escola Anna Nery, 2018
Objective: To understand adolescent's experiences with chronic renal failure disease, attended in a pubic teaching hospital at São Paulo state.
Marcela Astolphi de Souza, Luciana de Lione Melo   +1 more
doaj   +1 more source