Results 291 to 300 of about 210,758 (351)

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park   +22 more
wiley   +1 more source

Extent and Incidence of Pseudo‐Worsening of Kidney Function Due to Oral Antitumor Therapeutics in the AMBORA Cohort: An Analysis of Real‐World Data

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
A considerable number of oral antitumor therapeutics (OAT) has the potential for causing pseudo‐worsening of kidney function (PW) due to inhibition of renal creatinine secretion, i.e., kidney function is unaffected, while creatinine‐based calculation of glomerular filtration rate (eGFR) erroneously indicates an impaired kidney function.
Michael I. Sponfeldner   +13 more
wiley   +1 more source

[Chronic renal insufficiency. VIII. Comorbidity in renal insufficiency (RI)].

open access: yesNefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2002
A, Duque, H, García Pérez
openaire   +1 more source
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Chronic Renal Insufficiency

Pediatric Clinics of North America, 1976
Among the clinical disturbances attending chronic renal disease are water and electrolyte imbalances, acidosis, anemia, the toxicity arising from retention of wastes, and growth impairment. The pathogenesis of these abnormalities is discussed along with approaches to their management.
P R, Lewy, J K, Hurley
openaire   +4 more sources

Exophthalmus in Chronic Renal Insufficiency

Scandinavian Journal of Urology and Nephrology, 1971
The present results show that exophthalmus is a common symptom in chronic renal insufficiency. Thus, contrary to the norm, 19 (67%) of 28 clinically euthyroid, chronic dialysis patients displayed increased Hertel values. Tests of thyroid function in these patients indicated a reduced thyroxine-binding capacity of the serum protein and, in some cases, a
P, Schmidt   +3 more
openaire   +2 more sources

Digitalis in Chronic Renal Insufficiency

Blood Purification, 1985
Cardiac dysfunction is common in patients with terminal renal failure. However, no consensus has been reached with respect to the indications for digitalis therapy. Depression of myocardial contractility may occur as a result of circulating toxic factors, parathyroid hormone, and altered catecholaminergic responsiveness.
M, Rambausek, E, Ritz
openaire   +2 more sources

Polyneuropathy in Chronic Renal Insufficiency

JAMA: The Journal of the American Medical Association, 1965
Peripheral neuropathy is frequently associated with chronic renal insufficiency. It presents as progressive peripheral involvement first of sensory, then motor fibers. Loss of vibration sense is the most consistent early finding. Nerve conduction measurements aid in the detection of mild or subclinical neuropathy. Patients on long-term dialysis therapy
H A, TENCKHOFF   +3 more
openaire   +2 more sources

Renal Handling of Citrate in Chronic Renal Insufficiency

Nephron, 1991
Citrate is a relevant component of the inhibitory potential of the urine environment. Its excretion and renal handling have been widely studied in subjects with normal renal function, but little is known about changes induced by chronic renal insufficiency.
M, Marangella   +6 more
openaire   +2 more sources

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