Results 341 to 350 of about 419,069 (401)

Glutathione Threshold‐Triggered Selective Breakability of Organosilica Nanocapsules

ChemCatChem, EarlyView.
Replacing tetraethoxy orthosilicate (TEOS) by tetramethoxy orthosilicate (TMOS) as silica precursor to synthesize cleavable organosilica nanocapsules enabled the effective and selective entrapment of a positively charged protein as Cytochrome C (CytC) and a much more favorable breakability and kinetics release when exposed to high glutathione (GSH ...
Andrea Mosseri, Ana Rueda‐Flores, Jose L. Hueso, Esteban Urriolabeitia, Luisa De Cola, Jesus Santamaria   +5 more
wiley   +1 more source

Considerations in Transition of Pediatric Neurology Patients to Adult Care

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Transition refers to the planned, coordinated movement of adolescents from the child‐ and family‐centered environment of pediatric care to the adult healthcare system. A well‐structured transition process is essential for ensuring adolescents with chronic health conditions continue to thrive in young adulthood.
Asif Doja, Katherine Muir, Megan E. Harrison, Sarah Healy, Ashley Vandermorris, Alene Toulany   +5 more
wiley   +1 more source

Disposition and Absolute Bioavailability of Oral Imlunestrant in Healthy Women: A Phase 1, Open‐Label Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Imlunestrant (LY3484356) is a next‐generation orally bioavailable selective estrogen receptor degrader being investigated for the treatment of estrogen receptor–positive advanced breast and endometrial cancers. This Phase 1, open‐label, 2‐part study evaluated the disposition and absolute bioavailability of [14C]‐imlunestrant in 16 US‐based ...
Amita Datta‐Mannan, Boris Czeskis, Elaine Shanks, Eunice Yuen, Stephen Hall, Vivian Rodriguez Cruz, Kenneth Cassidy   +6 more
wiley   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams, Rosa Chan, Chad Orevillo, Gale O'Connell, Dewey McLin, Shikha Polega, Nuggehally R. Srinivas, Randall Kaye   +7 more
wiley   +1 more source

Advanced treatment for chronic renal insufficiency.

Nihon Naika Gakkai Zasshi, 1994
openaire   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Chronic Renal Insufficiency

Pediatric Clinics of North America, 1976
Among the clinical disturbances attending chronic renal disease are water and electrolyte imbalances, acidosis, anemia, the toxicity arising from retention of wastes, and growth impairment. The pathogenesis of these abnormalities is discussed along with approaches to their management.
Peter R. Lewy, John K. Hurley
openaire   +3 more sources

Exophthalmus in Chronic Renal Insufficiency

Scandinavian Journal of Urology and Nephrology, 1971
The present results show that exophthalmus is a common symptom in chronic renal insufficiency. Thus, contrary to the norm, 19 (67%) of 28 clinically euthyroid, chronic dialysis patients displayed increased Hertel values. Tests of thyroid function in these patients indicated a reduced thyroxine-binding capacity of the serum protein and, in some cases, a
G Prame, F Schittek, P Schmidt, N Stobaeus   +3 more
openaire   +3 more sources

Digitalis in Chronic Renal Insufficiency

Blood Purification, 1985
Cardiac dysfunction is common in patients with terminal renal failure. However, no consensus has been reached with respect to the indications for digitalis therapy. Depression of myocardial contractility may occur as a result of circulating toxic factors, parathyroid hormone, and altered catecholaminergic responsiveness.
Eberhard Ritz, M. Rambausek
openaire   +3 more sources

Polyneuropathy in Chronic Renal Insufficiency

JAMA: The Journal of the American Medical Association, 1965
Peripheral neuropathy is frequently associated with chronic renal insufficiency. It presents as progressive peripheral involvement first of sensory, then motor fibers. Loss of vibration sense is the most consistent early finding. Nerve conduction measurements aid in the detection of mild or subclinical neuropathy. Patients on long-term dialysis therapy
Robert H. Jebsen, Fred S. T. Boen, Heinrich A. Tenckhoff, John H. Spiegler   +3 more
openaire   +3 more sources

Calcifediol in Chronic Renal Insufficiency

JAMA: The Journal of the American Medical Association, 1976
To the Editor.— The reader who is not highly familiar with the recent developments concerning vitamin D and its various active forms may be misled by certain comments made (235: 164, 1976) by Teitelbaum and associates. First, the major reason for the interest in the treatment of renal osteodystrophy with 1,25-dihydroxycholecalciferol (1,25-dihydroxy ...
Anthony W. Norman, Jack W. Coburn
openaire   +5 more sources