Results 51 to 60 of about 435,562 (349)

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

High Fat High Cholesterol Diet (Western Diet) Aggravates Atherosclerosis, Hyperglycemia and Renal Failure in Nephrectomized LDL Receptor Knockout Mice: Role of Intestine Derived Lipopolysaccharide.

PLoS ONE, 2015
A high fat meal, frequently known as western diet (WD), exacerbates atherosclerosis and diabetes. Both these diseases are frequently associated with renal failure.
Siddhartha S Ghosh, Samuel Righi, Richard Krieg, Le Kang, Daniel Carl, Jing Wang, H Davis Massey, Domenic A Sica, Todd W B Gehr, Shobha Ghosh   +9 more
doaj   +1 more source

The eGFR-C study: accuracy of glomerular filtration rate (GFR) estimation using creatinine and cystatin C and albuminuria for monitoring disease progression in patients with stage 3 chronic kidney disease - prospective longitudinal study in a multiethnic population [PDF]

, 2014
Background: Uncertainty exists regarding the optimal method to estimate glomerular filtration rate (GFR) for disease detection and monitoring. Widely used GFR estimates have not been validated in British ethnic minority populations.
Sutton, AJ, Kevin Harris, eGFR-C study group (7648493), Khunti, Kamlesh, Brettell, Elizabeth A., Stevens, PE, Sutton, Andrew J., Claire C Sharpe, Lamb, EJ, Brettell, Elizabeth A, Cockwell, P, F. Loud (7648475), Sutton, Andrew J, P. E. Stevens (7648484), Sharpe, Claire C, Sharpe, CC, J. J. Deeks (7648466), Edmund J Lamb, Maarten W Taal, A. J. Sitch (7642292), Deeks, Jon J., R. S. Ottridge (7648478), Kamlesh Khunti, Elizabeth A Brettell, Taal, Maarten W., Khunti, K, Ottridge, Ryan, Lamb, Edmund J., Brettell, EA, Sutton, Andrew, Sharpe, Claire C., Ryan S Ottridge, Ottridge, Ryan S, ?, ?, N. Dalton (7648463), P. A. Kalra (7648472), Dalton, N, Kalra, PA, Neil Dalton, Taal, Maarten W, Taal, MW, Philip A Kalra, Sharpe, Claire C; id_orcid, Loud, F, K. Harris (75473), Tracy Higgins, Andrew J Sutton, Deeks, Jon J, Loud, Fiona, Dalton, Neil, Higgins, Tracy, Ottridge, RS, Higgins, T, Sitch, Alice J, Deeks, JJ, Sitch, AJ, M. W. Taal (7648490), T. Higgins (7648469), A. J. Sutton (7648487), Harris, Kevin, Kalra, Philip A, Paul Cockwell, Sitch, Alice J., Paul E Stevens, Ottridge, Ryan S., Harris, K, Deeks, Jonathan, Jon J Deeks, Stevens, Paul E., Sitch, Alice; id_orcid, E. J. Lamb (7648454), Kamlesh Khunti (171607), Fiona Loud, Stevens, Paul E, Kalra, Philip A., Alice J Sitch, Cockwell, Paul, P. Cockwell (7648460), Lamb, Edmund J, C. C. Sharpe (7648481), E. A. Brettell (7648457)   +80 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Association of Chronic Renal Insufficiency With In-Hospital Outcomes After Percutaneous Coronary Intervention

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2015
Background The association of chronic renal insufficiency with outcomes after percutaneous coronary intervention (PCI) in the current era of drug-eluting stents and modern antithrombotic therapy has not been well characterized.
Tanush Gupta, N. Paul, D. Kolte, P. Harikrishnan, S. Khera, W. Aronow, M. Mujib, C. Palaniswamy, Sachin S. Sule, D. Jain, Ali Ahmed, H. Cooper, W. Frishman, Deepak L. Bhatt, G. Fonarow, J. Panza   +15 more
semanticscholar   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Screening for chronic kidney disease in rural Malawi: results from a diabetic clinic

BMC Research Notes, 2019
Objective Patients with diabetes are at high risk of developing renal insufficiency and chronic kidney disease (CKD). As a result, screening for CKD is essential in diabetic patients as part of their care.
Chiyembekezo Kachimanga, Richard Kamwezi, Emily B. Wroe, Lawrence Nazimera, Enoch Ndarama, Limbani Thengo, George C. Talama   +6 more
doaj   +1 more source

Gut Microbiota-Dependent Trimethylamine N-oxide (TMAO) Pathway Contributes to Both Development of Renal Insufficiency and Mortality Risk in Chronic Kidney Disease

Circulation Research, 2014
Rationale: Trimethylamine-N-oxide (TMAO), a gut microbial-dependent metabolite of dietary choline, phosphatidylcholine (lecithin), and L-carnitine, is elevated in chronic kidney diseases (CKD) and associated with coronary artery disease pathogenesis ...
W. Tang, Zeneng Wang, David J. Kennedy, Yuping Wu, J. Buffa, Brendan Agatisa-Boyle, Xinmin S. Li, B. Levison, S. L. Hazen   +8 more
semanticscholar   +1 more source

Vitamin D and endothelial function in chronic kidney disease [PDF]

, 2014
PhDVitamin D deficiency in patients with chronic kidney disease, measured by reduced serum concentrations of 25 hydroxy vitamin D, is highly prevalent and associated with both endothelial dysfunction and an increased risk of cardiovascular disease ...
Dreyer, Gavin
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source