Results 201 to 210 of about 45,136 (281)

Tezepelumab Reduces Alarmin Cytokine Levels in Upper Airway Epithelial Cells in Patients With Severe Asthma

Clinical &Experimental Allergy, EarlyView.
Hazel Marriott, Adil Adatia, Subhabrata Moitra, Paige Lacy   +3 more
wiley   +1 more source

RNA binding protein ZFP36L1 promotes ferroptosis in chronic rhinosinusitis by destabilizing CAMK2A mRNA and impairing mitochondrial quality control

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
This graphical abstract illustrates the novel ZFP36L1–CAMK2A regulatory axis in chronic rhinosinusitis (CRS) pathogenesis: 1. Molecular initiation: In nasal epithelial cells, the RNA‐binding protein ZFP36L1 (upregulated in CRS) directly binds to AU‐rich elements (AREs) in the 3′‐untranslated region (3′‐UTR) of CAMK2A mRNA, promoting its degradation and
Jiayi Xiong, Shihan Zhang, Chunhua Li, Yufeng Ai, Xinru Liu, Yuxiang Liu, Hongbing Liu   +6 more
wiley   +1 more source

Geographic Disparities in Evidence Investigating the Use of Biologics in Chronic Rhinosinusitis. [PDF]

J Otolaryngol Head Neck Surg
Margulis I, Mohd Slim MA, Sommer EC, Haidar T, Abdallah Z, AlAmmar Y, Khalife S, Sommer DD.   +7 more
europepmc   +1 more source

Functional Endoscopic Sinus Surgery in Adults With CRSwNP Treated With Mepolizumab: Airway Physiology Outcomes From a Randomised Controlled Trial

Clinical &Experimental Allergy, EarlyView.
Jens Tidemandsen, Anne Sophie Homøe, Peter G. Gibson, Howraman Meteran, Kasper Aanæs, Morten Hostrup, Marie Høxbro, Vibeke Backer   +7 more
wiley   +1 more source

Elexacaftor–Tezacaftor–Ivacaftor Reduces Revision Sinus Surgery in People With Cystic Fibrosis

The Laryngoscope, Volume 136, Issue 5, Page 2048-2053, May 2026.
Elexacaftor–tezacaftor–ivacaftor (ETI) was associated with a significant decrease in the frequency and rate of endoscopic sinus surgeries in patients with cystic fibrosis. These findings suggest an improvement in CF‐related chronic rhinosinusitis outcomes following ETI and may influence future CF treatment decisions.
Amy Lin, Makanko Komara, Isaac Kistler, Zheng Hong Tan, Meredith Lind, Kavitha Kotha, Tendy Chiang   +6 more
wiley   +1 more source

GA2LEN sinusitis cohort study: chronic Rhinosinusitis with nasal polyps: differentiation based on chemokine pattern [PDF]

, 2011
Bachert, Claus, Cardell, Lars-Olaf, Fokkens, Wytske, Förster, Ulrike, Hellings, Peter, Kowalski, Marek, Mullol, Joaquim, Olze, Heidi, Tomassen, Peter, Toskala, Elina   +9 more
core   +1 more source

Diagnosing Eosinophilic Chronic Rhinosinusitis in Excised Tissue Using Optical Coherence Tomography

The Laryngoscope, Volume 136, Issue 5, Page 2092-2100, May 2026.
This study evaluated whether optical coherence tomography (OCT) can quantify eosinophils in excised sinonasal tissue and diagnose eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP). Counts of globules resembling eosinophils on OCT images strongly correlated with eosinophils per HPF on histology, with a cutoff of 45 globules on OCT imaging ...
Ido Badash, Michael Serafino, Adrian Correa, John S. Oghalai, Bozena Wrobel, Brian E. Applegate, Kevin Hur   +6 more
wiley   +1 more source

Chronic rhinosinusitis is a risk factor for interstitial lung disease in Sjogren's syndrome. [PDF]

BMC Pulm Med
Schonewald B, Xie C, Engel A, Summer R, Loizidis G.   +4 more
europepmc   +1 more source

Orbital Complications of Acute Rhinosinusitis in Adulthood: Predictors of Outcome and Management

The Laryngoscope, Volume 136, Issue 5, Page 2073-2081, May 2026.
In a multicenter cohort of 213 adults with orbital complications of acute rhinosinusitis, 68% required surgery and the modified Chandler classification was the strongest predictor of treatment modality. While abscess‐related and type II complications frequently necessitated surgical management, final ophthalmologic outcomes were uniformly favorable ...
Alessandro Vinciguerra, Vittorio Rampinelli, Mario Turri‐Zanoni, Marco Ferrari, Marco Valentini, Alberto Daniele Arosio, Federico Raimondi, Florian Chatelet, Stefano Taboni, Davide Mattavelli, Alberto Schreiber, Fabio Sovardi, Matteo Barucco, Lorena Di Girolami, Piergiorgio Gaudioso, Antonio Daloiso, Giulia Danè, Umberto Tanzini, Nicola Tessari, Jessica Zuppardo, Kays Burak Cakir, Yetkin Zeki Yilmaz, Yasar Unlu, Andrea Ronchi, Stefania Gallo, Francesca De Bernardi, Vasileios Chatzinakis, Argyro Leventi, Fabio Pagella, Benjamin Verillaud, Giuseppe Mercante, Apostolos Karligkiotis, Mario Bussi, Cesare Piazza, Alperen Vural, Paolo Castelnuovo, Piero Nicolai, Maurizio Bignami, Christos Georgalas, Iacopo Dallan, Philippe Herman, Paolo Battaglia   +41 more
wiley   +1 more source

The Therapeutic Role of Biologics in Chronic Rhinosinusitis with Nasal Polyps (CRSwNP): A Review of the Current Evidence. [PDF]

Ther Clin Risk Manag
Chen W, Wen Y, Wang J, Meng X, Su L, Wu Y.   +5 more
europepmc   +1 more source