Results 21 to 30 of about 2,745,887 (383)
Allergy. European Journal of Allergy and Clinical Immunology, 2021 The human monoclonal antibody dupilumab blocks interleukin (IL)‐4 andIL‐13, key and central drivers of type 2 inflammation. Dupilumab, on background mometasone furoate nasal spray (MFNS), improved outcomes in the phase III SINUS‐52 study (NCT02898454) in
S. Fujieda +13 more
semanticscholar +1 more source
Aeroallergen sensitization profile in medically resistant chronic rhinosinusitis
SAGE Open Medicine, 2020 Objectives: The aim of this study is to report the aeroallergen sensitization profile in medically resistant chronic rhinosinusitis with or without nasal polyps and its relationship to asthma.
Haitham Odat +2 more
doaj +1 more source
Chronic rhinosinusitis phenotypes [PDF]
Annals of Allergy, Asthma & Immunology, 2016 To review the current knowledge surrounding different chronic rhinosinusitis (CRS) presentations and the relative roles of nasal polyps, eosinophilia, and allergies in discerning phenotypes.PubMed literature review.Articles discussing the various phenotypes of CRS with emphasis on pathologic and immune mechanistic studies that distinguish disease ...
John W, Steinke, Larry, Borish
openaire +2 more sources
Development of Sinonasal Outcome Test (SNOT‐22) Domains in Chronic Rhinosinusitis With Nasal Polyps
The Laryngoscope, 2021 The 22‐item Sinonasal Outcome Test (SNOT‐22) is a validated chronic rhinosinusitis health‐related quality‐of‐life outcome (HRQoL) measure; however, SNOT‐22 domains have not been validated specifically for chronic rhinosinusitis with nasal polyps (CRSwNP).
Asif H Khan +9 more
semanticscholar +1 more source
Association of Menopause and Hormonal Contraceptive Use With Chronic Rhinosinusitis: An "All of Us" Analysis. [PDF]
Otolaryngol Head Neck SurgAbstract Objective The role of sex hormones in inflammation has attracted increased attention, but the impact of hormone‐modifying states in chronic rhinosinusitis (CRS) has not been thoroughly studied. We aim to investigate the association of menopause and systemic hormonal contraceptive (SHC) use with both CRS with (CRSwNP) and without (CRSsNP) nasal
Ahn A +5 more
europepmc +2 more sources
Chronic rhinosinusitis pathogenesis [PDF]
Journal of Allergy and Clinical Immunology, 2015 There are a variety of medical conditions associated with chronic sinonasal inflammation, including chronic rhinosinusitis (CRS) and cystic fibrosis. In particular, CRS can be divided into 2 major subgroups based on whether nasal polyps are present or absent.
Whitney W, Stevens +3 more
openaire +2 more sources
International Forum of Allergy and Rhinology, 2021 Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory disease treated with sinus surgery when refractory to medical intervention. However, recurrence postsurgery is common.
C. Hopkins +14 more
semanticscholar +1 more source
Possibilities of using combined drugs in the treatment of nasal obstruction syndrome
Медицинский совет, 2021 Introduction. The problem of chronic polypous rhinosinusitis today remains one of the most urgent in otorhinolaryngology. According to the analysis of medical documentation, diseases accompanied by this symptomatology are one of the most common reasons ...
S. V. Ryazantsev +2 more
doaj +1 more source
Therapeutic Strategies of Biologics in Chronic Rhinosinusitis: Current Options and Future Targets
International Journal of Molecular Sciences, 2022 Chronic rhinosinusitis is a chronic inflammatory disease of the upper airways, for which treatment options include medical or surgical therapy. However, there are limitations to conservative treatment strategies, such as the relapse of nasal polyps.
Junhu Tai, M. Han, Tae Hoon Kim
semanticscholar +1 more source
Elimination of pain improves specificity of clinical diagnostic criteria for adult chronic rhinosinusitis [PDF]
, 2017 Objective Determine whether the elimination of pain improves accuracy of clinical diagnostic criteria for adult chronic rhinosinusitis. Study Design Retrospective cohort study.
DiNardo, Laurence J. +4 more
core +2 more sources