Results 41 to 50 of about 65,941 (329)

Factor Analysis‐Based Quantitative Endotyping Improves Associations With CRS Cross‐Sectional and Longitudinal Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disease characterized by persistent sinonasal inflammation. There is increasing interest in endotype‐based classification, which categorizes CRS based on underlying inflammatory pathways.
Brooke N. Gleason, Zhidi Luo, Aditi Agarwal, Siyuan Dong, Regan L. Harmon, Junqin Bai, Chun‐Kang Liao, Julia Huang, David B. Conley, Kevin C. Welch, Robert C. Kern, Stephanie S. Smith, Anju T. Peters, Whitney S. Stevens, Atsushi Kato, Lutfiyya N. Muhammad, Bruce K. Tan   +16 more
wiley   +1 more source

Cross-sectional observational study on accessory ostium of the maxillary sinus

Journal of Clinical and Scientific Research, 2023
Background: The association between chronic sinusitis and accessory ostium (AO) is still a controversial subject as previous studies have given variable results with wider range.
Devendiran Rajendiran, Mohanbabu Nagabooshanam, Ravikumar Venugopal   +2 more
doaj   +1 more source

Machine Learning‐Enhanced Clinical Decision Support for Diagnosing Sinusitis With Nasal Endoscopy

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinusitis is a prevalent disease for which nasal endoscopy (NE) is an optimal diagnostic modality. However, NE accuracy is limited by inter‐operator variability in landmark identification and localization of mucus that is necessary for sinusitis diagnosis. We sought to develop a novel multi‐class machine learning (ML) framework that
Dipesh Gyawali, Thomas Mundy, Majid Hosseini, Morteza Bodaghi, Akio Fujiwara, Sejal Shyam Bhatia, Kayla Baker, Elena Bartolone, Dhara Patel, Henry Chu, Raju Gottumukkala, Jonathan Bidwell, Edward D. McCoul   +12 more
wiley   +1 more source

The role of harms and burdens in clinical practice guidelines: Lessons learned from the American Psychological Association's guideline development

Clinical Psychology: Science and Practice, EarlyView., 2020
Abstract Growing evidence supports the efficacy of various psychosocial interventions yet provides very little information about the potential harms and burdens of treatment. Lacking such information makes it difficult to make truly informed decisions about treatment options.
Raquel W. Halfond, Caroline Vaile Wright, Lynn F. Bufka   +2 more
wiley   +1 more source

Fungal speciation using quantitative polymerase chain reaction (QPCR) in patients with and without chronic rhinosinusitis. [PDF]

, 2006
Objectives/hypothesisThe objectives of this study were to determine the mycology of the middle meatus using an endoscopically guided brush sampling technique and polymerase chain reaction laboratory processing of nasal mucous; to compare the mycology of ...
Goldberg, Andrew N, Murr, Andrew H, Vesper, Stephen   +2 more
core  

Biologics for the treatment of chronic rhinosinusitis with nasal polyps : state of the art [PDF]

, 2019
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex upper airway disease affecting up to 11% of the population of Western Europe. In these western countries, 85% of the CRSwNP disease reveals a type 2 inflammatory pattern. In the last 15 years,
Bachert, Claus, Ren, Lei, Zhang, Luo, Zhang, Nan   +3 more
core   +1 more source

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai, Yongde Jin, Jingmei Chai, Jianing Yang, Jiangang Wang, Mu Chen, Liangchang Li, Chongyang Wang, Guanghai Yan   +8 more
wiley   +1 more source

Immunoglobulin IgG, IgM, IgA, and IgE Levels in Children with Chronic Sinusitis

Journal of Mazandaran University of Medical Sciences, 2020
Background and purpose: Sinusitis is a common disease in children that can lead to acute and chronic problems and sometimes severe complications. There is lack of evidence on underlying causes of chronic sinusitis in children in Iran, so, this study ...
Iraj Mohammadzadeh, Ali Mohammadpour Mir, , Ali Habibzadeh Bijani, Mohsen Mohammadi   +4 more
doaj  

Immunohistochemical changes of maxillary sinus mucosa with underlying adenomatous polyposis

Patologìâ, 2017
In maxillary sinusitis pathogenesis researchers paid much attention to the role of paranasal sinuses, sinus drainage dysfunctions, mucocyliary transport system disorders in cases of damage of sinuses mucous membranes.
Yu. M. Andreychyn, I. S. Kovalenko
doaj   +1 more source

Profiling risk factors for chronic uveitis in juvenile idiopathic arthritis: a new model for EHR-based research. [PDF]

, 2013
BackgroundJuvenile idiopathic arthritis is the most common rheumatic disease in children. Chronic uveitis is a common and serious comorbid condition of juvenile idiopathic arthritis, with insidious presentation and potential to cause blindness. Knowledge
Bauer-Mehren, Anna, Cole, Tyler S, Frankovich, Jennifer, Iyer, Srinivasan, Lependu, Paea, Shah, Nigam H   +5 more
core   +3 more sources