Results 61 to 70 of about 40,015 (285)

In Vivo Effects of N,N‐Diethyl‐Meta‐Toluamide (DEET) Exposure on Sinonasal Epithelia in a Murine Model

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Environmental factors, including airborne toxicants, are thought to contribute to the pathogenesis of chronic rhinosinusitis, although the exact mechanism is not fully understood. The purpose of this pilot study is to assess the impact of pesticide, N,N‐diethyl‐meta‐toluamide (DEET), on the sinonasal epithelium using an in vivo murine model ...
Jivianne T. Lee   +4 more
wiley   +1 more source

Evidence for a ‘preinvasive’ variant of fungal sinusitis: Tissue invasion without angioinvasion

open access: yesWorld Journal of Otorhinolaryngology-Head and Neck Surgery, 2017
Clinical experience has suggested the existence of an intermediate form of fungal sinusitis between the categories of non-invasive fungal sinusitis (non-IFS) and invasive fungal sinusitis (IFS). This fungal sinusitis variant demonstrates unhealthy mucosa
Hassan Paknezhad   +6 more
doaj   +1 more source

Impact of Early Versus Delayed Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis With Nasal Polyps

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Previous studies have suggested a benefit to early functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis (CRS). With the approval of T2 biologics for CRS with nasal polyps (CRSwNP), it is important to re‐evaluate FESS timing in relation to T2 biologic utilization.
Radhika Duggal   +4 more
wiley   +1 more source

Multidrug resistance pattern of bacterial agents isolated from patient with chronic sinusitis

open access: yesCaspian Journal of Internal Medicine, 2016
Background: Treatment of chronic sinusitis is complicated due to increase of antibiotic-resistant bacteria. The aim of this study was to determine the multidrug resistance (MDR) pattern of the bacteria causing chronic sinusitis in north of Iran. Methods:
Mohammad-sadegh Rezai   +3 more
doaj  

Radiofrequency Ablation Versus Laser Neurolysis of the Posterior Nasal Nerve in Patients With Chronic Rhinitis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare the clinical outcomes of radiofrequency ablation of the intraturbinate segment of the posterior nasal nerve (RAPN) alone versus combined RAPN with CO₂ laser posterior nasal nerve neurolysis (RPN3) in patients with chronic rhinitis refractory to medical therapy. Study Design Retrospective cohort study.
Chia‐Chen Lin   +5 more
wiley   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

open access: yesRheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen   +6 more
wiley   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou   +4 more
wiley   +1 more source

Obesity and Its Impact on Endoscopic Sinus Surgery Outcomes in Patients With Chronic Rhinosinusitis With Nasal Polyps

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy