Results 21 to 30 of about 8,283 (190)
Chronic spontaneous urticaria – a management pathway for patients with chronic spontaneous urticaria [PDF]
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2015 SummaryChronic spontaneous urticaria (CSU) is a common and challenging disease, especially with respect to healthcare provision in the context of the German statutory health insurance system. If treatment with second‐generation antihistamines is unsuccessful, current guidelines recommend further therapeutic options. However, most of these are off‐label.
Christian, Termeer +5 more
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Ligelizumab for Chronic Spontaneous Urticaria
New England Journal of Medicine, 2019 In the majority of patients with chronic spontaneous urticaria, most currently available therapies do not result in complete symptom control. Ligelizumab is a next-generation high-affinity humanized monoclonal anti-IgE antibody. Data are limited regarding the dose-response relationship of ligelizumab and the efficacy and safety of ligelizumab as ...
Marcus Maurer +26 more
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Remibrutinib in Chronic Spontaneous Urticaria
New England Journal of MedicineBackground: Chronic spontaneous urticaria is an idiopathic syndrome defined by recurring itch, hives, or angioedema (or a combination of these symptoms) for more than 6 weeks. Remibrutinib, an oral, highly selective Bruton's tyrosine kinase inhibitor, showed efficacy and favorable safety in phase 2b trials. Data from phase 3 trials are needed. Methods:
Metz, Martin +157 more
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The many faces of pediatric urticaria
Frontiers in Allergy, 2023 Urticaria is a common disease that can affect individuals of all age groups, with approximately one-quarter of the population experiencing it at least once in their lifetime.
Bulent Enis Sekerel +4 more
doaj +1 more source
Case Reports in Medicine, 2015 Chronic spontaneous urticaria is an itching skin disease characterised by wheals, angioedema, or both present for more than six weeks. Omalizumab is a humanized anti-IgE monoclonal antibody recently approved for treatment of chronic urticaria.
Misbah Nasheela Ghazanfar +1 more
doaj +1 more source
FEATURES OF IMMUNE RESPONSE AND BASOPHIL ACTIVATION IN CHILDREN WITH CHRONIC URTICARIA
Медицинская иммунология, 2015 Some features of peripheral bood basophil activation were studied in children with different types of chronic urticaria, in order to specify the sustaining mechanisms of chronic urticaria.
N. A. Sinelnikova +2 more
doaj +1 more source
Allergy, Asthma & Clinical Immunology, 2009 Urticaria is a group of diseases that share a distinct skin reaction pattern. Triggering of urticaria by infections has been discussed for many years but the exact role and pathogenesis of mast cell activation by infectious processes is unclear.
Wedi Bettina +3 more
doaj +1 more source
Treatment of Chronic Spontaneous Urticaria [PDF]
Allergy, Asthma & Immunology Research, 2012 Chronic spontaneous urticaria is defined as persistent symptoms of urticaria for 6 weeks or more. It is associated with autoimmunity in approximately 45 percent of patients. Therapy is often difficult however the initial approach should employ high-dose non-sedating antihistamines; 4-6 tablets/day may be necessary.
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Biologic drugs in chronic spontaneous urticaria.
Acta bio-medica : Atenei Parmensis, 2021 Chronic spontaneous urticaria (CSU) is a condition defined by the presence of recurrent urticaria, angioedema, or both, which persist for more than six weeks in duration and occurs in the absence of an identifiable trigger. Both children and adults can develop CSU, although it is more common in adults and in women than in men, with a peak occurrence in
Licari A. +9 more
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Acta Dermato-Venereologica, 2018 The association of atopic dermatitis and chronic spontaneous urticaria with socioeconomic status has been little studied. The aim of this study was to investigate the prevalence of skin diseases and their association with socioeconomic status in ...
Yi Xiao +15 more
doaj +1 more source