Results 71 to 80 of about 77,862 (256)

Autoimmune Theories of Chronic Spontaneous Urticaria [PDF]

Frontiers in Immunology, 2019
Urticaria (hives) is a highly prevalent skin disorder that can occur with or without associated angioedema. Chronic spontaneous urticaria (CSU) is a condition which persists for more than 6 weeks in duration and occurs in the absence of an identifiable provoking factor.
Sonali J. Bracken, Soman Abraham, Soman Abraham, Amanda S. MacLeod, Amanda S. MacLeod   +4 more
openaire   +3 more sources

Dupilumab in patients with chronic spontaneous urticaria (LIBERTY-CSU CUPID): two randomized, double-blind, placebo-controlled, phase 3 trials.

Journal of Allergy and Clinical Immunology
BACKGROUND Chronic spontaneous urticaria (CSU) is a chronic inflammatory disease characterized by recurrent pruritic wheals (hives) and/or angioedema. Patients with CSU could remain symptomatic despite standard-of-care H1-antihistamines (H1-AH) or anti ...
Marcus Maurer, T. Casale, Sarbjit S. Saini, M. Ben-Shoshan, A. Giménez-Arnau, J. Bernstein, Akiko Yagami, A. Stjepanovic, A. Radin, H. Staudinger, Naimish Patel, N. Amin, B. Akinlade, C. Fan, Deborah Bauer, G. Yancopouloš, K. Patel, L. Mannent, E. Laws   +18 more
semanticscholar   +1 more source

Chronic spontaneous urticaria: Focus on pathophysiology to unlock treatment advances

Allergy. European Journal of Allergy and Clinical Immunology, 2022
Chronic spontaneous urticaria (CSU) is a debilitating skin disease characterized by intensely itchy wheals, angioedema, or both. Symptoms recur spontaneously, on a near‐daily basis, over >6 weeks; many patients experience flare‐ups over several years and,
A. Kaplan, M. Lebwohl, A. Gimenez-Arnau, M. Hide, A. Armstrong, M. Maurer   +5 more
semanticscholar   +1 more source

Real‐World Safety and Effectiveness of Icatibant in Patients With Hereditary Angioedema (HAE): Post‐Marketing Surveillance in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Hereditary angioedema (HAE) is a rare, autosomal dominant, life‐threatening disease characterized by recurrent attacks of swelling of the face, upper airway, gastrointestinal tract, limbs, and/or genitalia. Genetic mutations of the SERPING1 gene encoding the C1‐inhibitor (C1‐INH) plasma protein are associated with HAE‐C1INH.
Kumiko Hosono, Miyako Hoshino
wiley   +1 more source

Long-term efficacy and safety of single-dose omalizumab in treating acute spontaneous urticaria

Allergy Medicine
Acute spontaneous urticaria has a high incidence, with sudden and severe symptoms that can significantly impact daily life and work. If not properly managed, it may lead to severe reactions such as angioedema, gastrointestinal symptoms, or even ...
Wen Chen, Mingyue Wang, Ruoyu Li
doaj   +1 more source

Case Report: Resolution of chronic urticaria following treatment of odontogenic infection [version 2; peer review: 2 approved, 1 approved with reservations]

F1000Research, 2019
Background: Chronic spontaneous urticaria (CSU) is a condition characterised by the presence of hives with/without angioedema, that affects individuals on more days than not for 6 weeks or more.
Susan Tadros, Sameer Bahal, Vasantha Nagendran   +2 more
doaj   +1 more source

Current and Future Approaches in Management of Chronic Spontaneous Urticaria Using Anti-IgE Antibodies

Medicina, 2022
Chronic spontaneous urticaria (CSU) considerably alters patients’ quality of life, often for extended periods, due to pruriginous skin lesions, impaired sleep, unexpected development of angioedema, and failure of conventional treatments in properly ...
Olguța Anca Orzan, Liliana Gabriela Popa, Mara Mădălina Mihai, Anca Cojocaru, Călin Giurcăneanu, Alexandra Maria Dorobanțu   +5 more
doaj   +1 more source

Case Report: Resolution of chronic urticaria following treatment of odontogenic infection [version 3; peer review: 2 approved, 1 approved with reservations]

F1000Research, 2019
Background: Chronic spontaneous urticaria (CSU) is a condition characterised by the presence of hives with/without angioedema, that affects individuals on more days than not for 6 weeks or more.
Susan Tadros, Sameer Bahal, Vasantha Nagendran   +2 more
doaj   +1 more source

Prevalence, treatment and burden of chronic spontaneous urticaria in five European countries

Journal of the European Academy of Dermatology and Venereology
Although chronic spontaneous urticaria (CSU) is a common form of chronic urticaria (CU), its impact on overall disease burden and treatment patterns in real‐world settings requires further understanding.
M. Balp, K. Krupsky, Shaloo Gupta, C. Lienhard, R. Kohli, Dhaval Patil, F. Tetart, John Reed, T. El-shanawany   +8 more
semanticscholar   +1 more source

Remibrutinib, a novel BTK inhibitor, demonstrates promising efficacy and safety in chronic spontaneous urticaria.

Journal of Allergy and Clinical Immunology, 2022
BACKGROUND Chronic spontaneous urticaria is inadequately controlled in many patients and severely impacts the quality of life. Remibrutinib, a highly selective, oral, novel covalent Bruton's tyrosine kinase inhibitor, might be effective in chronic ...
M. Maurer, W. Berger, A. Giménez-Arnau, K. Hayama, Vipul V. Jain, A. Reich, S. Haemmerle, K. Lheritier, P. Walsh, S. Xia, J. Storim   +10 more
semanticscholar   +1 more source