Results 291 to 300 of about 84,576 (334)

Sequential multimodal therapy in chronic thromboembolic pulmonary hypertension with mixed anatomical lesions: a proof of concept

European Respiratory Journal, 2023
Extract Three treatment options have been successfully developed for the management of chronic thromboembolic pulmonary hypertension (CTEPH): pulmonary endarterectomy (PEA), balloon pulmonary angioplasty (BPA) and pulmonary arterial hypertension (PAH ...
M. Jevnikar, S. Solinas, P. Brenot, B. Lechartier, M. Kularatne, D. Montani, L. Savale, Carlos Garcia-Alonso, Olivier Sitbon, A. Beurnier, A. Boucly, S. Bulifon, A. Seferian, A. Roche, O. Mercier, G. Simonneau, E. Fadel, Marc Humbert, X. Jaïs   +18 more
semanticscholar   +1 more source

Chronic thromboembolic pulmonary hypertension

Progress in Cardiovascular Diseases, 2002
Chronic thromboembolic pulmonary hypertension (CTEPH) should be differentiated from other etiologies of pulmonary hypertension since surgical intervention may be potentially curative. The presentation of this illness is nonspecific and may mimic other cardiopulmonary disease states.
Timothy L, Williamson, Nick H, Kim, Lewis J, Rubin   +2 more
openaire   +4 more sources

Chronic Thromboembolic Pulmonary Hypertension

Seminars in Respiratory and Critical Care Medicine, 1995
Remarkable advances have occurred over the past 2 decades in the diagnostic approach, surgical management, and postoperative care of patients afflicted with chronic thromboembolic pulmonary hypertension. Despite these advances, a great deal needs to be achieved if the morbidity and mortality of the disease process are to be reduced further.
P F, Fedullo, K M, Kerr, W R, Auger, S W, Jamieson, D P, Kapelanski   +4 more
openaire   +5 more sources

Chronic Thromboembolic Pulmonary Hypertension

New England Journal of Medicine, 2011
Currently, no pharmacologic regimen helps prevent chronic thromboembolic pulmonary hypertension, except anticoagulation with or without fibrinolysis. When administered in hemodynamically stable patients with right ventricular dysfunc- tion due to acute pulmonary embolism (submassive pulmonary embolism), fibrino- lytic therapy has been shown to reduce ...
Gregory, Piazza, Samuel Z, Goldhaber
openaire   +6 more sources

Chronic Thromboembolic Pulmonary Hypertension

Clinics in Chest Medicine, 2013
Chronic thromboembolic pulmonary hypertension (CTEPH) is a disease with high mortality and few treatment options. This article reviews the epidemiology of CTEPH and identifies risk factors for its development. The pathobiology and the progression from thromboembolic events to chronically increased right-sided pressures are discussed.
Peter S, Marshall, Kim M, Kerr, William R, Auger   +2 more
openaire   +2 more sources

Epigenetic Modification of the VWF Promotor Drives Platelet Aggregation on the Pulmonary Endothelium in Chronic Thromboembolic Pulmonary Hypertension.

American Journal of Respiratory and Critical Care Medicine, 2022
RATIONALE Von Willebrand Factor (VWF) mediates platelet adhesion during thrombosis. While chronic thromboembolic pulmonary hypertension (CTEPH) is associated with increased plasma levels of VWF, the role of this protein in CTEPH has remained enigmatic.
X. Manz, R. Szulcek, X. Pan, P. Symersky, Chris Dickhoff, J. Majolée, Veerle Kremer, Elisabetta Michielon, E. Jordanova, T. Radonic, I. Bijnsdorp, S. Piersma, T. Pham, C. Jiménez, A. Vonk Noordegraaf, F. D. de Man, R. Boon, J. Voorberg, P. Hordijk, J. Aman, H. Bogaard   +20 more
semanticscholar   +1 more source

Chronic Thromboembolic Pulmonary Disease and Chronic Thromboembolic Pulmonary Hypertension

Seminars in Respiratory and Critical Care Medicine, 2022
AbstractChronic thromboembolic pulmonary hypertension (CTEPH) and chronic thromboembolic pulmonary disease (CTEPD) are two terms characterizing symptomatic patients with chronic thromboembolic occlusions of pulmonary arteries with or without pulmonary hypertension at rest.
Remy, Martine, Hutt, Antoine, Remy, Jacques   +2 more
openaire   +3 more sources

Status and Future Directions for Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Disease With and Without Pulmonary Hypertension: A Scientific Statement From the American Heart Association

Circulation
Balloon pulmonary angioplasty continues to gain traction as a treatment option for patients with chronic thromboembolic pulmonary disease with and without pulmonary hypertension.
Vikas Aggarwal, Jay Giri, Scott H. Visovatti, Ehtisham Mahmud, Hiromi Matsubara, Michael M. Madani, Frances Rogers, Deepa Gopalan, Kenneth Rosenfield, Vallerie V. Mclaughlin   +9 more
semanticscholar   +1 more source

Chronic Thromboembolic Pulmonary Hypertension

Seminars in Respiratory and Critical Care Medicine, 2001
Over the past 4 decades, chronic thromboembolic pulmonary hypertension has evolved from an autopsy curiosity to a potentially correctable form of pulmonary hypertension. Approximately 2500 thromboendarterectomy procedures have now been performed worldwide with mortality rates reported by established programs experienced in the management of this ...
Peter, Fedullo, Kim M, Kerr, Nick H, Kim, William R, Auger   +3 more
openaire   +4 more sources

Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism

American Journal of Respiratory and Critical Care Medicine
Rationale Chronic thromboembolic pulmonary hypertension involves the formation and nonresolution of thrombus, dysregulated inflammation, angiogenesis, and the development of a small-vessel vasculopathy.
James Liley, M. Newnham, M. Bleda, K. Bunclark, William Auger, Joan A. Barberà, H. Bogaard, M. Delcroix, Timothy M. Fernandes, Luke Howard, D. Jenkins, Irene Lang, E. Mayer, Christopher J. Rhodes, Michael Simpson, L. Southgate, R. Trembath, J. Wharton, M. Wilkins, S. Gräf, Nicholas W. Morrell, J. Pepke Zaba, M. Toshner   +22 more
semanticscholar   +1 more source