Results 121 to 130 of about 188,117 (345)

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu, Junxia Zhang, Yusi Chen, Geng Shen, Yufei Han, Zihao Zhou, Jinxuan Chen, Xuya Kang, Huilin Qu, Jiaxin Duanmu, Haibao Shang, Yingjia Li, Wei Huang, Yan Zhang   +13 more
wiley   +1 more source

Efficacy and safety of Tornus catheter in percutaneous coronary intervention of hard or balloon-uncrossable chronic total occlusion

ARYA Atherosclerosis, 2016
BACKGROUND: Balloon advancement and dilation through chronic total occlusion segment could be challenging in some cases after successful wire crossing.
Mohsen Mohandes, Sergio Rojas, Jordi Guarinos, Francisco Fernández, Xavier Oliva, Marianela Noueched, Alfredo Bardaji   +6 more
doaj  

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

The Feasibility of Imaging Myocardial Ischemic/Reperfusion Injury Using \u3csup\u3e99m\u3c/sup\u3eTc-labeled Duramycin in a Porcine Model [PDF]

, 2015
When pathologically externalized, phosphatidylethanolamine (PE) is a potential surrogate marker for detecting tissue injuries. 99mTc-labeled duramycin is a peptide-based imaging agent that binds PE with high affinity and specificity.
Audi, Said H., Fang, Wei, Holly, Thomas A., Johnson, Steven E., Lee, Daniel C., Wang, Feng, Wang, Lei, Zhao, Ming, Zhu, Bao, Zhu, Haibo, Zimmer, Michael   +10 more
core   +1 more source

Volumetric Additive Manufacturing of Dormant Catalytic Chemistries to Generate Silicone Micro‐ and Millifluidic Devices and Instant Molds

Advanced Science, EarlyView.
We describe use of a novel zero‐dose approach to tomographic volumetric additive manufacturing that has enabled us to print silicone micro‐ and millifluidic devices and instant molds within minutes. The silicones are polymerized using photoactivated dormant platinum photohydrosilylation catalysts that would traditionally be difficult to access in ...
Johanna A. Vandenbrande, Martin P. De Beer, Erika J. Fong, Aftab Bhanvadia, Massimiliano Ferrucci, Wilson Kong, Daniel Wang, Ryan M. Hensleigh, Michell Marufu, James S. Oakdale, Fangyou Xie, Maxim Shusteff, Johanna J. Schwartz   +12 more
wiley   +1 more source

Chronic Total Occlusions

JACC: Cardiovascular Interventions, 2017
Leibundgut, Gregor, Kaspar, Mathias
openaire   +4 more sources

The Effect of ACE Inhibition on the Pulmonary Vasculature in Combined Models of Chronic Hypoxia and Pulmonary Arterial Banding in Sprague Dawley Rats [PDF]

, 2010
Microfocal CT was used to image the pulmonary arterial (PA) tree in rodent models of pulmonary hypertension (PH). CT images were used to measure the arterial tree diameter along the main arterial trunk at several hydrostatic intravascular pressures and ...
Baumgardt, Shelley, Clarke, Shanelle, Molthen, Robert C.   +2 more
core   +1 more source

Recanalization of the Chronically Occluded Internal Carotid Artery: Review of the Literature. [PDF]

, 2020
Introduction: We reviewed the literature on interventions for patients with medically refractory chronically occluded internal carotid artery (COICA) to assess the risks and/or benefits after recanalization via an endovascular technique (ET) or hybrid ...
Hasan, David M., Jabbour, Pascal, Roa, Jorge A., Samaniego, Edgar A., Zanaty, Mario   +4 more
core   +1 more source

P5538Meta-analysis of the impact on mortality of successful revascularization of the non-infarct-related artery coronary chronic total occlusion in patients with acute myocardial infarction treated by PPCI [PDF]

, 2017
T.O.N.G. Jiangtao, Yuliang Qian, L.I. Chenggang, Su Xiaojuan, Yong Xia   +4 more
openalex   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source