Results 161 to 170 of about 188,117 (345)

Oxidative stress and inflammation: Early predictive indicators of multiple recurrent coronary in‐stent chronic total occlusions in elderly patients after coronary stenting [PDF]

, 2020
Xia Li, Hualan Zhou, Dianxuan Guo, Youdong Hu, Xiang Fang, Ying Chen, Fenglin Zhang   +6 more
openalex   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

The Comparison of Long-Term Outcome Between Patients with Single and Multiple Coronary Chronic Total Occlusions After Percutaneous Coronary Intervention

, 2022
Miaomiao Cao, Bolin Li, Qian Li, Chaofeng Sun   +3 more
openalex   +1 more source

Effect of Revascularization on Coronary Chronic Total Occlusion in Patients Undergoing Coronary Artery Bypass Grafting [PDF]

, 2021
Yun Seok Kim, Jiyun Lee, Hwan Wook Kim, Joonkyu Kang, Hyun Song, Ju Yong Lim   +5 more
openalex   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

Feasibility and Safety of Reversed Wire Technique in Coronary Chronic Total Occlusion Interventions [PDF]

, 2019

openalex   +1 more source

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

Advanced Science, EarlyView.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang, Ran Yan, Lede Lin, Lei Xiang, Xiaozhi Xia, Liao Peng, Xiaoshuai Gao, Jiawei Chen, Yang Xiong, Liang Zhou, Yunfeng Lin   +10 more
wiley   +1 more source

The hybrid algorithm in treatment of coronary chronic total occlusions – MSWiA Lublin CTO 5-year registry

Advances in Interventional Cardiology, 2020
Jakub Drozd, Marcin Kowalski, Tomasz Wołyniak, Monika Zaręba-Giezek   +3 more
doaj   +1 more source

Role of pre-procedure CCTA in predicting failed percutaneous coronary intervention for chronic total occlusions [PDF]

Hua Zhou, Xiaojun Fan, Mingyuan Yuan, Wei Wang, Qiyuan Wu   +4 more
openalex   +1 more source

“Time Is Brain” – for Cell Therapies

Advanced Science, EarlyView.
The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin, Dominikus Brian, Rebecca Z. Weber, Patrick D. Lyden, Ruslan Rust   +4 more
wiley   +1 more source