Results 271 to 280 of about 543,327 (389)

Disruption of the Blood–Brain Barrier Predicts Progression of Cerebral Small Vessel Disease White Matter Hyperintensities

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to test if blood–brain barrier (BBB) disruption, detected using dynamic susceptibility contrast (DSC) imaging, would predict progression of white matter hyperintensities (WMHs) over the subsequent year in patients with chronic cerebrovascular disease. Methods The study included patients with a history of stroke
Richard Leigh   +4 more
wiley   +1 more source

Basiliximab in the Prophylaxis of aGVHD for Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Thalassemia Major: A Prospective, Multicenter, Open‐Label, Randomized Controlled Study

open access: yes
American Journal of Hematology, EarlyView.
Zhenbin Wei   +19 more
wiley   +1 more source

Prospective, Multicenter Evaluation of Transcarotid Artery Revascularization in Standard‐Risk Patients: 30‐Day Outcomes of the ROADSTER 3 Study

open access: yesAnnals of Neurology, EarlyView.
Objective To evaluate the real‐world safety and efficacy for standard surgical risk patients with extracranial internal carotid artery disease undergoing transcarotid artery revascularization. Methods ROADSTER 3 is a prospective, multicenter, single‐arm post‐approval study.
Jeffrey Jim   +15 more
wiley   +1 more source

Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions

open access: yesAngewandte Chemie, EarlyView.
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan   +3 more
wiley   +2 more sources

Chronic Total Occlusion Trials

open access: yesJACC: Cardiovascular Interventions, 2017
Manesh R. Patel, J. Antonio Gutierrez
openaire   +1 more source

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

open access: yesAnnals of Neurology, EarlyView.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito   +10 more
wiley   +1 more source

Tin—Tin π Bonding as a Conduit for Alkali‐Metal Reduction

open access: yesAngewandte Chemie, EarlyView.
Reactions of the doubly reduced distannynes, [Ar′SnSnAr′M2], (Ar′ = C6H3‐2,6‐Dipp; M ═ ′Li, Na, K), with the successively heavier alkali metals (M) result in reduction of M, which is proposed to occur via a suitably disposed π* SOMO of the putative radical anions, [Ar′SnSnAr′M2]•−.
Agustín Morales   +5 more
wiley   +2 more sources

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