Results 81 to 90 of about 2,716,837 (401)
British Journal of Clinical Pharmacology, EarlyView.Aims Adverse drug reactions (ADRs) are a key driver of missed doses of anti‐tuberculosis (TB) therapy. We aimed to determine the relative burden of ADR‐driven missed doses, the missed dose patterns associated with ADRs, and the association between specific ADRs and missed doses.
Eleanor G. Dixon +10 more
wiley +1 more source
Recovery of smell sense loss by mepolizumab in a patient allergic to dermatophagoides and affected by chronic rhinosinusitis with nasal polyps [PDF]
, 2019 Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) frequently presents with dysfunction or loss of the sense of smell, resulting in a signifcant impairment in quality of life.
Cavaliere, Carlo +7 more
core +1 more source
Navigating adverse immunostimulation: A practical guide for clinical researchers
British Journal of Clinical Pharmacology, EarlyView.Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort +3 more
wiley +1 more source
Higher Levels of Depression and Anxiety in Patients with Chronic Urticaria
Medical Science Monitor, 2019 Background Chronic urticaria (CU) is a common disease, characterized by the development of wheals, angioedema, or both. CU reduces quality of life and can also cause emotional distress.
T. S. Tat
semanticscholar +1 more source
Evaluation of anxiety in children diagnosed with chronic urticaria
Medicine ScienceThis study aimed to evaluate anxiety levels in children diagnosed with chronic urticaria and to compare them with those in a healthy control group. Designed as a cross-sectional study, it included children aged 9–18 years diagnosed with chronic urticaria
Ugur Altas +6 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang +6 more
wiley +1 more source
Altered Gut Microbiota Diversity and Composition in Chronic Urticaria
Disease Markers, 2019 Background The pathogenesis of chronic urticaria (CU) is closely related to imbalances in immunity. The gastrointestinal microflora provides a vast and continuous stimulation for the immune system. However, the composition and diversity of gut microflora
Tao Lu +8 more
semanticscholar +1 more source
Chemistry &Biodiversity, EarlyView.ABSTRACT The increasing inadequacy of antibiotics against multidrug‐resistant pathogens is a growing concern. In this study, the antibacterial activity of propolis extracts with different phenolic profiles against carbapenem‐resistant clinical isolates was investigated.
Ülkü Zeynep Esertaş +3 more
wiley +1 more source
Impact of chronic urticaria on quality of life and work in Japan: Results of a real‐world study
Journal of dermatology (Print), 2018 Little attention has been given to the burden of chronic urticaria (CU) in Japan compared with other skin diseases, such as atopic dermatitis (AD) and psoriasis.
Asako Itakura +3 more
semanticscholar +1 more source
Chronic urticaria in children: Etiologies, Clinical Manifestations, Diagnosis and Treatment
Journal of Pediatrics Review, 2013 Chronic urticaria is defined as a skin disease with central induration (wheal) and erythema formation around it (flare) that appears at least twice a week and remains at least for 6 weeks continually. The incidence of urticaria in children is about 0.1-3%
Javad Ghaffari +4 more
doaj +2 more sources