Results 201 to 210 of about 1,617,912 (396)

From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases

International Wound Journal, 2017
R. Serra, L. Gallelli, Lucia Butrico, Gianluca Buffone, F. Caliò, G. De Caridi, M. Massara, A. Barbetta, B. Amato, Miriam Labonia, S. Mimmi, E. Iaccino, S. de Franciscis   +12 more
semanticscholar   +1 more source

FBXO44 Regulates FOXP1 Degradation Through AURKA‐Dependent Phosphorylation to Promote Colorectal Cancer Progression

Advanced Science, EarlyView.
FBXO44 promotes colorectal cancer progression by targeting FOXP1 for ubiquitin‐mediated degradation. This study reveals a phosphorylation‐dependent mechanism involving AURKA and highlights the FBXO44/FOXP1/Cyclin E2 axis as a potential therapeutic target in colorectal cancer.
Hongxu Nie, Hengjie Xu, Sheng Yang, Chuanxin Tian, Tuo Wang, Chi Jin, Zhihao Chen, Xiaowei Wang, Junwei Tang, Yifei Feng, Yueming Sun   +10 more
wiley   +1 more source

Relationship between Arterial and Venous Blood Gases in Patients Presenting with Chronic Obstructive Pulmonary Disease

, 2018
Muhammad Nusrullah, Muhammad Younus, Yasir Nasir   +2 more
openalex   +2 more sources

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

Advanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan, Yinghao Hong, Xiangjun Ji, Jing Xiang, Jinxi Liu, Lixin Liang, Meng Ren, Wenhan Chen, Tengfei Xu, Zhijie Li, Tieliu Shi, Yong Jiang, Huaping Liang, Jinghua Liu   +13 more
wiley   +1 more source

Sex Differences Regarding the Risk of Incident Venous Thromboembolism in Hospitalized Patients with an Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Jiaqi Pu, Qun Yi, Yuanming Luo, Hailong Wei, Huiqing Ge, Huiguo Liu, Jianchu Zhang, Xianhua Li, Pinhua Pan, Xin Xie, Mengqiu Yi, Lina Cheng, Hui Zhou, Jiarui Zhang, Lige Peng, Jiaxin Zeng, Xueqing Chen, Haixia Zhou   +17 more
openalex   +1 more source

Chronic Venous Disease Management Update

, 2012
Md Saif Ullah Khan, Mohammad Safiuddin, Md Mahbubur Rahman   +2 more
openalex   +2 more sources

Obesity‐Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis

Advanced Science, EarlyView.
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang, Chong Yang, Dayuan Luo, Pingting Liu, Zhen Zeng, Weilin Peng, Dongzi Peng, Hao Su, Xiaoxiong Xiao, Haiqin Wang, Xin Jin   +10 more
wiley   +1 more source

Thrombotic complications of central venous catheterization with peripherally inserted catheters in patients with classical-Hodgkin lymphoma. [PDF]

Hemasphere
Picardi M, Giordano C, Vincenzi A, Scarpa A, Pugliese N, Della Pepa R, Pane F.   +6 more
europepmc   +1 more source

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

Advanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu, Zhe Wang, Diwei Zheng, Yongfang Zheng, Zhiwu Jiang, Jiang Lv, Yueqin Zhu, Heng Jia, Ziyuan Duan, Tingjie Yuan, Qiting Wu, Youguo Long, Shouheng Lin, Yao Yao, Georgia Carson, Jean P. Thiery, Kwan Man, Peng Li   +17 more
wiley   +1 more source

Trends in Patient Reported Outcomes of Conservative and Surgical Treatment of Primary Chronic Venous Disease Contradict Current Practices [PDF]

, 2011
Fedor Lurie, Robert L. Kistner
openalex   +1 more source