Results 271 to 280 of about 318,409 (361)

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Outcomes Following Iliac Vein Stenting for Non-Thrombotic Iliac Vein Lesions-A Narrative Review Based on Large Sample Studies. [PDF]

J Funct Biomater
Jayaraj A.
europepmc   +1 more source

Physical activity in patients with chronic venous insufficiency: Its relation with disease severity, pain, fatigue, and functionality

Gamze Aydın, E. Çiftçi, Emine Atıcı, Ahmet Cüneyt Akgöl, Mehmet Altuğ TUNCER   +4 more
openalex   +2 more sources

Tumors of the liver [PDF]

, 1995
Iwatsuki, S, Starzl, TE
core  

Plant Robotics for Sustainable and Environmentally Friendly Robots: Insights from Actuation Characteristics

Advanced Science, EarlyView.
Plants are promising materials for building sustainable and eco‐friendly robots due to their inherent multifunctionality, with actuation playing a crucial role. This article focuses on the physical movements of plants and, from the perspective of actuation characteristics, explores representative plant species and their behaviors, the current state of ...
Kazuya Murakami, Misao Sato, Yu Ikeda, Tatsuhiro Horii, Yukari Nagatoshi, Miki Fujita, Toshinori Fujie, Yasunari Fujita, Jun Shintake   +8 more
wiley   +1 more source

Pulmonary Embolism in Antiphospholipid Syndrome (APS)-Where Are We and Where Are We Going? [PDF]

Int J Mol Sci
Lucki M, Grygiel-Górniak B, Lucka E, Lesiak M, Araszkiewicz A.   +4 more
europepmc   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

Post-Thrombotic Syndrome: Pathophysiology, Clinical Implications, and Advances in Management. [PDF]

Health Sci Rep
Htun T, Amrutiya R, Win KHH.
europepmc   +1 more source

Referee report. For: Reliability, validity, and minimal clinically important differences for the Thai-version of the Aberdeen Varicose Vein Questionnaire (AVVQ-Thai) in patients with chronic venous disease [version 1; peer review: 1 approved]

Nawaphan Taengsakul
openalex   +1 more source

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

Advanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu, Chen Su, Jianling Liu, Mingyan Xing, Xiaoxia Wu, Lingxia Wang, Xiaoming Zhao, Hanwen Zhang, YangYang Xie, YangYang Wang, Hong Li, Yu Li, Ming Li, Haibing Zhang   +13 more
wiley   +1 more source