Results 81 to 90 of about 318,409 (361)

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION: NEW ASPECTS OF THE DEVELOPMENT AND PROGRESSION OF THE DISEASE

open access: yesKlinicist, 2014
The review presents data on the incidence of chronic thromboembolic pulmonary hypertension after pulmonary thromboembolism and describescongenital and acquired coagulation abnormalities in patients with venous thromboembolism.
A. A. Klimenko   +3 more
doaj   +3 more sources

An Out‐of‐Place Etiology: Recognizing FMR1 Premutation in the Memory Clinic

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The FMR1 gene premutation (55–200 CGG repeats) is usually associated with a wide range of symptoms and phenotypes within the Fragile X‐tremor/ataxia syndrome (FXTAS), but may also manifest as predominant or isolated cognitive decline. We describe three male patients referred for progressive cognitive impairment and behavioral changes. Standard
Guido Greco   +7 more
wiley   +1 more source

Application of phlebotropic therapy. A review of current clinical practice in Russia

open access: yesАмбулаторная хирургия, 2017
The current understanding of the development and course of pathological processes in chronic vascular diseases implies a widespread use of medications.
M. N. Kudykin
doaj  

Generation of an induced pluripotent stem cell line from a patient with Varicose veins

open access: yesStem Cell Research
Chronic venous disease is among the most common vascular diseases globally. Varicose veins (VV), characterized by permanent dilation, elongation, and tortuosity of superficial veins, is a manifestation of chronic venous disease.
Chikage Noishiki   +10 more
doaj   +1 more source

Efeito da actividade física na insuficiência venosa crónica dos membros inferiores.

open access: yesActa Médica Portuguesa, 2008
Chronic venous disease of the lower limbs is one of the most commonly reported medical conditions and a substancial source of morbidity. The aim or the present work was to assess the influence of the physical activity on chronic venous insufficiency of ...
Luiz Ronaldo Alberti   +3 more
doaj   +1 more source

Thromboembolic and neurologic sequelae of discontinuation of an antihyperlipidemic drug during ongoing warfarin therapy [PDF]

open access: yes, 2017
Warfarin and antihyperlipidemics are commonly co-prescribed. Some antihyperlipidemics may inhibit warfarin deactivation via the hepatic cytochrome P450 system.
Bilker, Warren B.   +5 more
core   +2 more sources

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Peculiarities of drug therapy of lower extremities chronic venous insufficiency

open access: yesАмбулаторная хирургия, 2016
Chronic vein diseases (CVD) depending on the design and evaluation criteria of conducted epidemiologic studies are diagnosed in 20-85% of adult residents of industrially developed countries.
V. Y. Bogachev   +3 more
doaj  

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