Results 131 to 140 of about 174,741 (390)

The place of subfascial endoscopic perforator vein surgery (SEPS) in advanced chronic venous insufficiency treatment

Videosurgery and Other Miniinvasive Techniques, 2011
In spite of medical science development and initiation of new technologies in minimally invasive surgery, treatmentof advanced chronic venous insufficiency at the 5th and 6th degree of CEAP classification is still a great clinical challenge.In case of no
Wiesław Pesta, Waldemar Kurpiewski, Marek Kowalczyk, Rafał Szynkarczuk, Magdalena Łuba, Anna Żurada, Radosław Grabysa   +6 more
doaj  

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

Advanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan, Yinghao Hong, Xiangjun Ji, Jing Xiang, Jinxi Liu, Lixin Liang, Meng Ren, Wenhan Chen, Tengfei Xu, Zhijie Li, Tieliu Shi, Yong Jiang, Huaping Liang, Jinghua Liu   +13 more
wiley   +1 more source

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

Advanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu, Zhe Wang, Diwei Zheng, Yongfang Zheng, Zhiwu Jiang, Jiang Lv, Yueqin Zhu, Heng Jia, Ziyuan Duan, Tingjie Yuan, Qiting Wu, Youguo Long, Shouheng Lin, Yao Yao, Georgia Carson, Jean P. Thiery, Kwan Man, Peng Li   +17 more
wiley   +1 more source

Chronic Venous Insufficiency and Dystrophic Subcutaneous Calcification

Acta Médica Portuguesa, 2019
N/A.
Sara Castelo Branco, Mylene Costa, Alexandre Vasconcelos   +2 more
doaj   +1 more source

Does air plethysmography correlate with duplex scanning in patients with chronic venous insufficiency? [PDF]

, 1993
Paul S. van Bemmelen, Mark A. Mattos, Kim J. Hodgson, Lynne D. Barkmeier, Don E. Ramsey, William E. Faught, David S. Sumner   +6 more
openalex   +1 more source

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

Advanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou, Yuqing Lv, Lin Li, Shukui Zhang, Jiaqi Liang, Chengchao Wu, Enyu Huang, Jianwei Jiao, Jingjing Zhang   +8 more
wiley   +1 more source

Experience in the use of wound-healing collagen dressings in the complex treatment of venous trophic ulcers

Лечащий Врач
Background. Venous trophic ulcers are a typical manifestation of decompensation of chronic venous insufficiency of the lower extremities. The causes of venous trophic ulcers are chronic vein diseases such as varicose veins of the lower limbs, pelvis ...
A. V. Teplikov, A. I. Cherepanin
doaj   +1 more source

Immunohistochemical Localization of Factor XIIIa in Chronic Venous Insufficiency [PDF]

, 1994
Wolfgang Vanscheidt, A. Laubert, H. Laaff, Johannes M. Weiss, Erwin Schöpf   +4 more
openalex   +1 more source

Strategic Design of Aptamer‐Guided Aggregation‐Induced Emission Nanoparticles for Targeted Photodynamic Therapy in Breast Cancer

Advanced Science, EarlyView.
This study presents MF3Ec‐TBPP nanoparticles for targeted photodynamic therapy of Luminal A breast cancer. These nanoparticles combine an AIE‐based photosensitizer with an aptamer. Tests show they effectively inhibit tumor growth while protecting healthy tissue via aggregation and dipalmitoylphosphatidylcholine, indicating potential for improved ...
Charlie C. H. Ma, Qingqing Liu, Yue Sui, Wutong Du, Kristy W. K. Lam, Jacky W. Y. Lam, Chao Li, Tengteng Chen, Jianwei Sun, Nuomin Li, Ryan T. K. Kwok, Jianping Chen, Feiyi Sun, Ben Zhong Tang   +13 more
wiley   +1 more source

The effect of passage number on fibroblast cellular senescence in patients with chronic venous insufficiency with and without ulcer [PDF]

, 1999
J.D. Raffetto, Manuel V. Mendez, Tania J. Phillips, Hee‐Young Park, James O. Menzoı́an   +4 more
openalex   +1 more source