Results 171 to 180 of about 159,120 (369)

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

open access: yesAdvanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park   +9 more
wiley   +1 more source

Living Biotherapeutics Using Nanoparticles‐Armed Cyanobacteria for Boosting Photodynamic‐Immunotherapy of Cancer

open access: yesAdvanced Science, EarlyView.
A schematic illustration of the cyanobacteria‐based biohybrid platform for photodynamic cancer therapy enhanced PDT. The platform continuously outputs O2 (to alleviate tumor hypoxia) and 1O2 (for tumor treatment), achieving improved photodynamic immunotherapy. Abstract The interdisciplinary development of synthetic biology and material sciences propels
Zhengwei Xu   +14 more
wiley   +1 more source

NEW TRENDS IN SURGICAL MANAGEMENT OF CHRONIC VENOUS INSUFICIENCY OF LOWER LIMBS

open access: yesZdravniški Vestnik, 2002
Background. Chronic venous insufficiency is the disease of modern world. Indications for surgical treatment of varicose veins are reviewed. Elucidated are methods of extirpation of varicose veins, safenofemoral and safenopopliteal ligature.Conclusions ...
Vladimir Valentinuzzi
doaj  

Endovenous thermal ablation for healing venous ulcers and preventing recurrence. [PDF]

open access: yes, 2013
Carradice, D   +4 more
core   +1 more source

Single‐Cell RNA Sequencing Identifies MMP11+ Cancer‐Associated Fibroblasts as Drivers of Angiogenesis and Bladder Cancer Progression

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing identifies MMP11⁺ CAFs as pro‐angiogenic cells accumulating during bladder cancer progression. These cells promote angiogenesis by regulating ESM1⁺ tip endothelial cells and recruiting SPP1⁺ macrophages. Tumor‐derived BMP2 promotes their activation.
Wuwu Xu   +13 more
wiley   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

open access: yesAdvanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan   +16 more
wiley   +1 more source

Implantable Biophotonic Device for Wirelessly Cancer Real‐Time Monitoring and Modulable Treatment

open access: yesAdvanced Science, EarlyView.
A wirelessly implantable biophotonic device is capable of distinguishing tumors and evaluating their progression by monitoring sO2 levels indicative of the tumor hypoxic microenvironment. Additionally, this device is not only employed for in situ PDT but also for concurrent monitoring of chemotherapy and PDT progress, thereby enabling the evaluation ...
Renhao Nie   +8 more
wiley   +1 more source

Надфасціальна перфорантотомія у комплексному лікуванні хворих з трофічними виразками нижніх кінцівок венозного генезу [PDF]

open access: yes, 2011
Представлен опыт оперативного лечения 3681 больных с различными формами и степенями ХВН за период с 1993 по 2010 годы.The article presented the experience of operative treatment of 3891 patients with various forms and degrees of chronic venous ...
Войтановський, І.М.   +4 more
core  

An Off‐the‐Shelf Artificial Blood Clot Hydrogel Neutralizing Multiple Proinflammatory Mediators for Pro‐Regenerative Periodontitis Treatment

open access: yesAdvanced Science, EarlyView.
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy