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This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li +9 more
wiley +1 more source
Various Therapies for Lymphedema and Chronic Venous Insufficiency, Including a Multimodal At-Home Nonpneumatic Compression Treatment. [PDF]
Barnhart H, Maldonado T, Rockson SG.
europepmc +1 more source
Efficacy of complex decongestive therapy on venous flow, internal saphenous diameter, edema, fat mass of the limbs and quality of life in patients with chronic venous insufficiency: A randomized clinical trial. [PDF]
Martín Jiménez A +7 more
europepmc +1 more source
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Circulation, 2014
Varicose veins are a common manifestation of chronic venous disease and affect approximately 25% of adults in the western hemisphere. The historical standard treatment has been surgery, with high ligation and stripping, combined with phlebectomies. In the past decade, alternative treatments such as endovenous ablation of the great saphenous vein (GSV ...
Robert T Eberhardt, Joseph D Raffetto
exaly +3 more sources
Varicose veins are a common manifestation of chronic venous disease and affect approximately 25% of adults in the western hemisphere. The historical standard treatment has been surgery, with high ligation and stripping, combined with phlebectomies. In the past decade, alternative treatments such as endovenous ablation of the great saphenous vein (GSV ...
Robert T Eberhardt, Joseph D Raffetto
exaly +3 more sources
Chronic Venous Insufficiency Disease
Chronic venous insufficiency is a debilitating condition. It affects about 0.2% of the population and is very demanding on health resources. In the UK, there are about 100,000 patients with active leg ulcers and treating these patients costs the national health service between £100 and £400,000,000 per anum.
S. Shami, S. Sarin, J. Scurr
openaire +2 more sources
Improving Adherence to Wearing Compression Stockings for Chronic Venous Insufficiency and Venous Leg Ulcers: A Scoping Review [PDF]
Purpose: Patient adherence to wearing compression stockings in the management of chronic venous insufficiency (CVI) and venous leg ulcers (VLUs) is low. Poor adherence with compression stockings contributes to recurrence and impaired healing of VLUs.
Laila Bar +2 more
exaly +2 more sources
Evaluation of inflammatory cell biomarkers in chronic venous insufficiency
Objective Inflammation has been implicated as a factor that may contribute to chronic venous insufficiency. The purpose of this study is to compare readily available inflammatory cell biomarkers, with an emphasis on neutrophil count, lymphocyte count ...
Carl D Shrader, Ashley B Petrone
exaly +2 more sources
2022
Chronic venous insufficiency (CVI) is a significant cause of lower leg edema. It is caused by progressively worsening vein valve incompetence and luminal abnormalities leading to a negative cycle of sustained uncompensated venous hypertension. The sequalae of chronic venous hypertension involve further vein damage, cumulative reduction of venous return
Kumar, Varun N., Tripathi, Ramesh K.
openaire +2 more sources
Chronic venous insufficiency (CVI) is a significant cause of lower leg edema. It is caused by progressively worsening vein valve incompetence and luminal abnormalities leading to a negative cycle of sustained uncompensated venous hypertension. The sequalae of chronic venous hypertension involve further vein damage, cumulative reduction of venous return
Kumar, Varun N., Tripathi, Ramesh K.
openaire +2 more sources
Surgical Clinics of North America, 1990
Like the noninvasive assessment of arterial occlusive disease, the various methods for evaluation of chronic venous insufficiency (CVI) can be divided into those that provide hemodynamic information and those that provide anatomic detail. The majority of noninvasive methods for evaluation of CVI are directed toward assessing hemodynamic events in large
T F, O'Donnell +2 more
openaire +2 more sources
Like the noninvasive assessment of arterial occlusive disease, the various methods for evaluation of chronic venous insufficiency (CVI) can be divided into those that provide hemodynamic information and those that provide anatomic detail. The majority of noninvasive methods for evaluation of CVI are directed toward assessing hemodynamic events in large
T F, O'Donnell +2 more
openaire +2 more sources

