Establishment of a novel cynomolgus monkey model of hyperuricemia
We established a novel hyperuricemia model in cynomolgus monkeys (A) via oral administration of potassium oxonate, hydrochlorothiazide, and adenine mixed in fruits and vegetables. This model (B) targets uric acid synthesis and enzymatic degradation, and (C) regulates renal and intestinal excretion, thereby stably elevating serum uric acid and serving ...
Ji‐Wei Wang +12 more
wiley +1 more source
Challenges of modeling pristane‐induced lupus in non‐human primates
Systemic lupus erythematosus (SLE) in cynomolgus monkeys was modeled by two intraperitoneal injections of pristane at a dose of 3.5 mL/kg, administered at weeks 1 and 23. Serum samples from all monkeys that received pristane tested positive for antinuclear antibodies.
Elena Vladimirovna Vinogradova +5 more
wiley +1 more source
Various Therapies for Lymphedema and Chronic Venous Insufficiency, Including a Multimodal At-Home Nonpneumatic Compression Treatment. [PDF]
Barnhart H, Maldonado T, Rockson SG.
europepmc +1 more source
ABSTRACT The paper establishes an advanced computing algorithm to investigate the thermosolutal dynamics of an electrically conductive Brinkman‐type nanofluid that moves in a porous channel, and the fluid is acted on by an inclined magnetic field exerted externally.
Urwa Shehbaz +4 more
wiley +1 more source
Evaluation of the dynamic thiol/disulfide homeostasis in patients with chronic venous insufficiency. [PDF]
Muduroglu A +11 more
europepmc +1 more source
Chronic cerebrospinal venous insufficiency (CCSVI) and multiple sclerosis - PRO.
Miro Denišlič
openalex +1 more source
Early Pliocene Varanus (Squamata, Varanidae) remains from Megalo Emvolon, Thessaloniki, Greece
The article describes new cranial and postcranial varanid material from Megalo Emvolon Lower Pliocene vertebrate fossil site near Thessaloniki. The fossils, likely representing a single individual, are referred to Varanus cf. marathonensis. Abstract This study describes new fossil varanid material from a recently discovered fossil spot (MVL site) at ...
Chara Drakopoulou +3 more
wiley +1 more source
The flip-flops sandal sign: A semiotic evidence of chronic venous insufficiency in patients with stasis dermatitis. [PDF]
da Silva GAR +2 more
europepmc +1 more source
Abstract In birds, the neural canal houses a variety of anatomical structures including the spinal cord, meninges, spinal vasculature, and respiratory diverticula. Among these, paramedullary diverticula and the extradural dorsal spinal vein may leave behind osteological correlates in the form of pneumatic foramina and fossae, and a bilobed geometry of ...
Jessie Atterholt +5 more
wiley +1 more source
Efficacy of complex decongestive therapy on venous flow, internal saphenous diameter, edema, fat mass of the limbs and quality of life in patients with chronic venous insufficiency: A randomized clinical trial. [PDF]
Martín Jiménez A +7 more
europepmc +1 more source

