Results 111 to 120 of about 122,830 (307)
DEPLOYING INTEGRATED CARE MODELS FOR FRAIL ELDERLY PATIENTS
International Journal of Integrated Care, 2015 Marisa Merino +9 more
doaj +3 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Etudes EpistémèThis article focuses on the use and theories of mineral waters to explore how healing can be understood as a multifaceted phenomenon by doctors and patients alike. In medical theory and practice around taking the waters, health improvements were expected
Sophie Vasset
doaj +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Constipation and encopresis in children [PDF]
, 2010 Chronic constipation is defined as a decrease in frequency or the painful passage of bowel movements present for several weeks. Retentive encopresis is the term reserved for the involuntary and uncontrollable soiling that occurs in children with chronic ...
Aquilina, Samuel, Attard, Thomas
core
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
A cornerstone of healthy aging: do we need to rethink the concept of adherence in the elderly?
Patient Preference and Adherence, 2018 Anna Giardini,1 Marina Maffoni,2 Przemyslaw Kardas,3 Elisio Costa4 1Psychology Unit, Istituti Clinici Scientifici Maugeri Spa SB, IRCSS Montescano, Montescano (PV), Italy; 2Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy;
Giardini A, Maffoni M, Kardas P, Costa E
doaj
Relating Severe Poverty and Chronic Poverty [PDF]
The severely poor are very poor since their consumption is far below the absolute poverty line, and the chronically poor are very poor since their consumption persists for long periods below the absolute poverty line. A combination of chronic poverty and
Shahin Yaqub
core
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Coping and Management Techniques Used by Chronic Low Back Pain Patients Receiving Treatment From Chiropractors. [PDF]
, 2019 OBJECTIVES:The purpose of this study was to describe coping strategies (eg, mechanisms, including self-treatment) that a person uses to reduce pain and its impact on functioning as reported by patients with chronic low back pain who were seen by doctors ...
Coulter, Ian D +6 more
core +1 more source