Results 251 to 260 of about 74,054 (305)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Emerging use of pulmonary artery and cardiac pressure sensing technology in the management of worsening heart failure events. [PDF]

Heart Fail Rev
Mace MI, Lala A, Fendler TJ, Sauer AJ.
europepmc   +1 more source

News Coverage of the Proposed Menthol Cigarette Ban in the United States (2022-2024) - a Content Analysis. [PDF]

Nicotine Tob Res
Wackowski OA, Garmon J, Altunbilek A, Johnson A, Ganz O, Ntansah CA, Fryer CS, Villanti AC, Sterling KL.   +8 more
europepmc   +1 more source