Results 111 to 120 of about 171,099 (284)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Wine Growing Has Had Role in County History Article [PDF]
, 2015 Douglas County Museum curator George Abdill chronicles the history of grape growing in the region, including the first families: Applegate, Von Passl, and Doerner. Abdill speculates there is still missing information about the history of Oregon wine, and
Abdill, George
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
“Of the Ruin and Conquest of Britain”: The Anglo-Saxon Transformation of the British Isles
, 2015 The history of Britain after the collapse of the Western Roman Empire has traditionally been perceived as one of invasion and domination at the hands of Germanic peoples most commonly known as the Angles, Saxons, and Jutes.
Caswell, Bryan G.
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Expressions, Summer 2018 [PDF]
, 2018 College of Humanities and the Arts ...
San Jose State University, College of the Humanities and the Arts
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Filología, 2014 En las últimas décadas, las aproximaciones críticas y retóricas al archivo colonial hispanoamericano han puesto en cuestión las nociones mismas de “autor”, “texto”, “literatura” entre otras.
Valeria Añón
doaj
Is the Book Really Better?: Comparing the Facets of Fantasy Apparent in C.S. Lewis\u27s \u3ci\u3eThe Lion, the Witch and the Wardrobe\u3c/i\u3e and its 2005 Cinematic Adaptation [PDF]
, 2019 “Once there were four children whose names were Peter, Susan, Edmund and Lucy. This story is about something that happened to them when they were sent away from London during the war because of the air-raids” (Lewis 2).
Manzano, Brianna J
core +1 more source